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Dietary tryptophan metabolite released by intratumoral Lactobacillus reuteri facilitates immune checkpoint inhibitor treatment.
Bender MJ, McPherson AC, Phelps CM, Pandey SP, Laughlin CR, Shapira JH, Medina Sanchez L, Rana M, Richie TG, Mims TS, Gocher-Demske AM, Cervantes-Barragan L, Mullett SJ, Gelhaus SL, Bruno TC, Cannon N, McCulloch JA, Vignali DAA, Hinterleitner R, Joglekar AV, Pierre JF, Lee STM, Davar D, Zarour HM, Meisel M. Bender MJ, et al. Among authors: bruno tc. Cell. 2023 Apr 27;186(9):1846-1862.e26. doi: 10.1016/j.cell.2023.03.011. Epub 2023 Apr 6. Cell. 2023. PMID: 37028428 Free PMC article.
Expression of lymphoid structure-associated cytokine/chemokine gene transcripts in tumor and protein in serum are prognostic of melanoma patient outcomes.
Karapetyan L, AbuShukair HM, Li A, Knight A, Al Bzour AN, MacFawn IP, Thompson ZJ, Chen A, Yang X, Dadey R, Karunamurthy A, De Stefano DV, Sander C, Kunning SR, Najjar YG, Davar D, Luke JJ, Gooding W, Bruno TC, Kirkwood JM, Storkus WJ. Karapetyan L, et al. Among authors: bruno tc. Front Immunol. 2023 Jun 22;14:1171978. doi: 10.3389/fimmu.2023.1171978. eCollection 2023. Front Immunol. 2023. PMID: 37435077 Free PMC article.
Getting to YES: The Evolution of the University of Pittsburgh Medical Center Hillman Cancer Center Youth Enjoy Science (YES) Academy.
Ayoob JC, Boyce RD, Livshits S, Bruno TC, Delgoffe GM, Galson DL, Duncan AW, Atkinson JM, Oesterreich S, Evans S, Alikhani M, Baker TA, Pratt S, DeHaan KJ, Chen Y, Boone DN. Ayoob JC, et al. Among authors: bruno tc. J STEM Outreach. 2022;5(2):10.15695/jstem/v5i2.02. doi: 10.15695/jstem/v5i2.02. Epub 2022 Aug 3. J STEM Outreach. 2022. PMID: 36910569 Free PMC article.
All-trans retinoic acid induces durable tumor immunity in IDH-mutant gliomas by rescuing transcriptional repression of the CRBP1-retinoic acid axis.
Rao A, Zhang X, Cillo AR, Sussman JH, Sandlesh P, Tarbay AC, Mallela AN, Cardello C, Krueger K, Xu J, Li A, Xu J, Patterson J, Akca E, Angione A, Jaman E, Kim WJ, Allen J, Venketeswaran A, Zinn PO, Parise R, Beumer J, Duensing A, Holland EC, Ferris R, Bagley SJ, Bruno TC, Vignali DAA, Agnihotri S, Amankulor NM. Rao A, et al. Among authors: bruno tc. bioRxiv [Preprint]. 2024 Apr 13:2024.04.09.588752. doi: 10.1101/2024.04.09.588752. bioRxiv. 2024. PMID: 38645178 Free PMC article. Preprint.
Integrated BATF transcriptional network regulates suppressive intratumoral regulatory T cells.
Shan F, Cillo AR, Cardello C, Yuan DY, Kunning SR, Cui J, Lampenfeld C, Williams AM, McDonough AP, Pennathur A, Luketich JD, Kirkwood JM, Ferris RL, Bruno TC, Workman CJ, Benos PV, Vignali DAA. Shan F, et al. Among authors: bruno tc. Sci Immunol. 2023 Sep 15;8(87):eadf6717. doi: 10.1126/sciimmunol.adf6717. Epub 2023 Sep 15. Sci Immunol. 2023. PMID: 37713508
Tumor cell p38 inhibition to overcome immunotherapy resistance.
Luke JJ, Dadey RE, Augustin RC, Newman S, Singh KB, Doerfler R, Behr S, Lee P, Isett B, Deitrick C, Li A, Joy M, Reeder C, Smith K, Urban J, Sellitto L, Jelinek M, Christner SM, Beumer JH, Villaruz LC, Kulkarni A, Davar D, Poklepovic AS, Najjar Y, Zandberg DP, Soloff AC, Bruno TC, Vujanović L, Skinner HD, Ferris RL, Bao R. Luke JJ, et al. Among authors: bruno tc. Res Sq [Preprint]. 2023 Aug 19:rs.3.rs-3183496. doi: 10.21203/rs.3.rs-3183496/v1. Res Sq. 2023. PMID: 37645831 Free PMC article. Preprint.
A Novel Humanized Immune Stroma PDX Cancer Model for Therapeutic Studies.
Yang D, Beddows I, Tang H, Cascio S, McGonigal SC, Bai S, Johnson BK, Powers JJ, Acharya R, Bao R, Bruno TC, Soong TR, Conejo-Garcia JR, Shen H, Bility MT, Buckanovich RJ. Yang D, et al. Among authors: bruno tc. bioRxiv [Preprint]. 2023 Jul 3:2023.07.03.547206. doi: 10.1101/2023.07.03.547206. bioRxiv. 2023. PMID: 37461447 Free PMC article. Preprint.
72 results