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Dietary tryptophan metabolite released by intratumoral Lactobacillus reuteri facilitates immune checkpoint inhibitor treatment.
Bender MJ, McPherson AC, Phelps CM, Pandey SP, Laughlin CR, Shapira JH, Medina Sanchez L, Rana M, Richie TG, Mims TS, Gocher-Demske AM, Cervantes-Barragan L, Mullett SJ, Gelhaus SL, Bruno TC, Cannon N, McCulloch JA, Vignali DAA, Hinterleitner R, Joglekar AV, Pierre JF, Lee STM, Davar D, Zarour HM, Meisel M. Bender MJ, et al. Among authors: gocher demske am. Cell. 2023 Apr 27;186(9):1846-1862.e26. doi: 10.1016/j.cell.2023.03.011. Epub 2023 Apr 6. Cell. 2023. PMID: 37028428 Free PMC article.
IFNγ-induction of TH1-like regulatory T cells controls antiviral responses.
Gocher-Demske AM, Cui J, Szymczak-Workman AL, Vignali KM, Latini JN, Pieklo GP, Kimball JC, Avery L, Cipolla EM, Huckestein BR, Hedden L, Meisel M, Alcorn JF, Kane LP, Workman CJ, Vignali DAA. Gocher-Demske AM, et al. Nat Immunol. 2023 May;24(5):841-854. doi: 10.1038/s41590-023-01453-w. Epub 2023 Mar 16. Nat Immunol. 2023. PMID: 36928412 Free PMC article.
Catch and release: freeing up PD-L1 ameliorates autoimmunity.
Grebinoski S, Gocher-Demske AM, Vignali DAA. Grebinoski S, et al. Among authors: gocher demske am. Nat Immunol. 2022 Mar;23(3):344-346. doi: 10.1038/s41590-022-01140-2. Nat Immunol. 2022. PMID: 35190718 Free PMC article.