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Biological brain age prediction using machine learning on structural neuroimaging data: Multi-cohort validation against biomarkers of Alzheimer's disease and neurodegeneration stratified by sex.
Cumplido-Mayoral I, García-Prat M, Operto G, Falcon C, Shekari M, Cacciaglia R, Milà-Alomà M, Lorenzini L, Ingala S, Meije Wink A, Mutsaerts HJMM, Minguillón C, Fauria K, Molinuevo JL, Haller S, Chetelat G, Waldman A, Schwarz AJ, Barkhof F, Suridjan I, Kollmorgen G, Bayfield A, Zetterberg H, Blennow K, Suárez-Calvet M, Vilaplana V, Gispert JD; ALFA study; EPAD study; ADNI study; OASIS study. Cumplido-Mayoral I, et al. Among authors: cacciaglia r. Elife. 2023 Apr 17;12:e81067. doi: 10.7554/eLife.81067. Elife. 2023. PMID: 37067031 Free PMC article.
Effects of APOE-ε4 allele load on brain morphology in a cohort of middle-aged healthy individuals with enriched genetic risk for Alzheimer's disease.
Cacciaglia R, Molinuevo JL, Falcón C, Brugulat-Serrat A, Sánchez-Benavides G, Gramunt N, Esteller M, Morán S, Minguillón C, Fauria K, Gispert JD; ALFA study. Cacciaglia R, et al. Alzheimers Dement. 2018 Jul;14(7):902-912. doi: 10.1016/j.jalz.2018.01.016. Epub 2018 Mar 28. Alzheimers Dement. 2018. PMID: 29605385 Free article.
White matter microstructure is altered in cognitively normal middle-aged APOE-ε4 homozygotes.
Operto G, Cacciaglia R, Grau-Rivera O, Falcon C, Brugulat-Serrat A, Ródenas P, Ramos R, Morán S, Esteller M, Bargalló N, Molinuevo JL, Gispert JD; ALFA Study. Operto G, et al. Among authors: cacciaglia r. Alzheimers Res Ther. 2018 May 24;10(1):48. doi: 10.1186/s13195-018-0375-x. Alzheimers Res Ther. 2018. PMID: 29793545 Free PMC article.
Longitudinal structural cerebral changes related to core CSF biomarkers in preclinical Alzheimer's disease: A study of two independent datasets.
Falcon C, Tucholka A, Monté-Rubio GC, Cacciaglia R, Operto G, Rami L, Gispert JD, Molinuevo JL; Alzheimer's Disease Neuroimaging Initiative. Falcon C, et al. Among authors: cacciaglia r. Neuroimage Clin. 2018 Apr 16;19:190-201. doi: 10.1016/j.nicl.2018.04.016. eCollection 2018. Neuroimage Clin. 2018. PMID: 30023169 Free PMC article.
Centiloid cut-off values for optimal agreement between PET and CSF core AD biomarkers.
Salvadó G, Molinuevo JL, Brugulat-Serrat A, Falcon C, Grau-Rivera O, Suárez-Calvet M, Pavia J, Niñerola-Baizán A, Perissinotti A, Lomeña F, Minguillon C, Fauria K, Zetterberg H, Blennow K, Gispert JD; Alzheimer’s Disease Neuroimaging Initiative, for the ALFA Study. Salvadó G, et al. Alzheimers Res Ther. 2019 Mar 21;11(1):27. doi: 10.1186/s13195-019-0478-z. Alzheimers Res Ther. 2019. PMID: 30902090 Free PMC article.
APOE-ε4 risk variant for Alzheimer's disease modifies the association between cognitive performance and cerebral morphology in healthy middle-aged individuals.
Cacciaglia R, Molinuevo JL, Falcón C, Sánchez-Benavides G, Gramunt N, Brugulat-Serrat A, Esteller M, Morán S, Fauria K, Gispert JD; ALFA study. Cacciaglia R, et al. Neuroimage Clin. 2019;23:101818. doi: 10.1016/j.nicl.2019.101818. Epub 2019 Apr 8. Neuroimage Clin. 2019. PMID: 30991302 Free PMC article.
65 results