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Page 1
Biological brain age prediction using machine learning on structural neuroimaging data: Multi-cohort validation against biomarkers of Alzheimer's disease and neurodegeneration stratified by sex.
Cumplido-Mayoral I, García-Prat M, Operto G, Falcon C, Shekari M, Cacciaglia R, Milà-Alomà M, Lorenzini L, Ingala S, Meije Wink A, Mutsaerts HJMM, Minguillón C, Fauria K, Molinuevo JL, Haller S, Chetelat G, Waldman A, Schwarz AJ, Barkhof F, Suridjan I, Kollmorgen G, Bayfield A, Zetterberg H, Blennow K, Suárez-Calvet M, Vilaplana V, Gispert JD; ALFA study; EPAD study; ADNI study; OASIS study. Cumplido-Mayoral I, et al. Among authors: mila aloma m. Elife. 2023 Apr 17;12:e81067. doi: 10.7554/eLife.81067. Elife. 2023. PMID: 37067031 Free PMC article.
Amyloid beta, tau, synaptic, neurodegeneration, and glial biomarkers in the preclinical stage of the Alzheimer's continuum.
Milà-Alomà M, Salvadó G, Gispert JD, Vilor-Tejedor N, Grau-Rivera O, Sala-Vila A, Sánchez-Benavides G, Arenaza-Urquijo EM, Crous-Bou M, González-de-Echávarri JM, Minguillon C, Fauria K, Simon M, Kollmorgen G, Zetterberg H, Blennow K, Suárez-Calvet M, Molinuevo JL; ALFA study. Milà-Alomà M, et al. Alzheimers Dement. 2020 Oct;16(10):1358-1371. doi: 10.1002/alz.12131. Epub 2020 Jun 23. Alzheimers Dement. 2020. PMID: 32573951 Free PMC article.
Association of years to parent's sporadic onset and risk factors with neural integrity and Alzheimer biomarkers.
Arenaza-Urquijo EM, Salvadó G, Operto G, Minguillón C, Sánchez-Benavides G, Crous-Bou M, Grau-Rivera O, Sala-Vila A, Falcón C, Suárez-Calvet M, Zetterberg H, Blennow K, Gispert JD, Molinuevo JL; ALFA Study. Arenaza-Urquijo EM, et al. Neurology. 2020 Oct 13;95(15):e2065-e2074. doi: 10.1212/WNL.0000000000010527. Epub 2020 Jul 31. Neurology. 2020. PMID: 32737076 Free PMC article.
Novel tau biomarkers phosphorylated at T181, T217 or T231 rise in the initial stages of the preclinical Alzheimer's continuum when only subtle changes in Aβ pathology are detected.
Suárez-Calvet M, Karikari TK, Ashton NJ, Lantero Rodríguez J, Milà-Alomà M, Gispert JD, Salvadó G, Minguillon C, Fauria K, Shekari M, Grau-Rivera O, Arenaza-Urquijo EM, Sala-Vila A, Sánchez-Benavides G, González-de-Echávarri JM, Kollmorgen G, Stoops E, Vanmechelen E, Zetterberg H, Blennow K, Molinuevo JL; ALFA Study. Suárez-Calvet M, et al. EMBO Mol Med. 2020 Dec 7;12(12):e12921. doi: 10.15252/emmm.202012921. Epub 2020 Nov 10. EMBO Mol Med. 2020. PMID: 33169916 Free PMC article.
Association of weight change with cerebrospinal fluid biomarkers and amyloid positron emission tomography in preclinical Alzheimer's disease.
Grau-Rivera O, Navalpotro-Gomez I, Sánchez-Benavides G, Suárez-Calvet M, Milà-Alomà M, Arenaza-Urquijo EM, Salvadó G, Sala-Vila A, Shekari M, González-de-Echávarri JM, Minguillón C, Niñerola-Baizán A, Perissinotti A, Simon M, Kollmorgen G, Zetterberg H, Blennow K, Gispert JD, Molinuevo JL; ALFA Study. Grau-Rivera O, et al. Alzheimers Res Ther. 2021 Feb 17;13(1):46. doi: 10.1186/s13195-021-00781-z. Alzheimers Res Ther. 2021. PMID: 33597012 Free PMC article.
Cerebral amyloid-β load is associated with neurodegeneration and gliosis: Mediation by p-tau and interactions with risk factors early in the Alzheimer's continuum.
Salvadó G, Milà-Alomà M, Shekari M, Minguillon C, Fauria K, Niñerola-Baizán A, Perissinotti A, Kollmorgen G, Buckley C, Farrar G, Zetterberg H, Blennow K, Suárez-Calvet M, Molinuevo JL, Gispert JD; ALFA study. Salvadó G, et al. Alzheimers Dement. 2021 May;17(5):788-800. doi: 10.1002/alz.12245. Epub 2021 Mar 4. Alzheimers Dement. 2021. PMID: 33663013 Free PMC article.
DHA intake relates to better cerebrovascular and neurodegeneration neuroimaging phenotypes in middle-aged adults at increased genetic risk of Alzheimer disease.
Sala-Vila A, Arenaza-Urquijo EM, Sánchez-Benavides G, Suárez-Calvet M, Milà-Alomà M, Grau-Rivera O, González-de-Echávarri JM, Crous-Bou M, Minguillón C, Fauria K, Operto G, Falcón C, Salvadó G, Cacciaglia R, Ingala S, Barkhof F, Schröder H, Scarmeas N, Gispert JD, Molinuevo JL; ALFA study. Sala-Vila A, et al. Am J Clin Nutr. 2021 Jun 1;113(6):1627-1635. doi: 10.1093/ajcn/nqab016. Am J Clin Nutr. 2021. PMID: 33733657 Free PMC article.
Amyloid-β positive individuals with subjective cognitive decline present increased CSF neurofilament light levels that relate to lower hippocampal volume.
Sánchez-Benavides G, Suárez-Calvet M, Milà-Alomà M, Arenaza-Urquijo EM, Grau-Rivera O, Operto G, Gispert JD, Vilor-Tejedor N, Sala-Vila A, Crous-Bou M, González-de-Echávarri JM, Minguillon C, Fauria K, Simon M, Kollmorgen G, Zetterberg H, Blennow K, Molinuevo JL; ALFA Study. Sánchez-Benavides G, et al. Neurobiol Aging. 2021 Aug;104:24-31. doi: 10.1016/j.neurobiolaging.2021.02.026. Epub 2021 Mar 6. Neurobiol Aging. 2021. PMID: 33962331 Free article.
Cognitively unimpaired individuals with a low burden of Aβ pathology have a distinct CSF biomarker profile.
Milà-Alomà M, Shekari M, Salvadó G, Gispert JD, Arenaza-Urquijo EM, Operto G, Falcon C, Vilor-Tejedor N, Grau-Rivera O, Sala-Vila A, Sánchez-Benavides G, González-de-Echávarri JM, Minguillon C, Fauria K, Niñerola-Baizán A, Perissinotti A, Simon M, Kollmorgen G, Zetterberg H, Blennow K, Suárez-Calvet M, Molinuevo JL; ALFA study. Milà-Alomà M, et al. Alzheimers Res Ther. 2021 Jul 27;13(1):134. doi: 10.1186/s13195-021-00863-y. Alzheimers Res Ther. 2021. PMID: 34315519 Free PMC article. Clinical Trial.
35 results