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KaryoCreate: A CRISPR-based technology to study chromosome-specific aneuploidy by targeting human centromeres.
Bosco N, Goldberg A, Zhao X, Mays JC, Cheng P, Johnson AF, Bianchi JJ, Toscani C, Di Tommaso E, Katsnelson L, Annuar D, Mei S, Faitelson RE, Pesselev IY, Mohamed KS, Mermerian A, Camacho-Hernandez EM, Gionco CA, Manikas J, Tseng YS, Sun Z, Fani S, Keegan S, Lippman SM, Fenyö D, Giunta S, Santaguida S, Davoli T. Bosco N, et al. Among authors: zhao x. Cell. 2023 Apr 27;186(9):1985-2001.e19. doi: 10.1016/j.cell.2023.03.029. Epub 2023 Apr 18. Cell. 2023. PMID: 37075754 Free PMC article.
Immune evasion in HPV- head and neck precancer-cancer transition is driven by an aneuploid switch involving chromosome 9p loss.
William WN Jr, Zhao X, Bianchi JJ, Lin HY, Cheng P, Lee JJ, Carter H, Alexandrov LB, Abraham JP, Spetzler DB, Dubinett SM, Cleveland DW, Cavenee W, Davoli T, Lippman SM. William WN Jr, et al. Among authors: zhao x. Proc Natl Acad Sci U S A. 2021 May 11;118(19):e2022655118. doi: 10.1073/pnas.2022655118. Proc Natl Acad Sci U S A. 2021. PMID: 33952700 Free PMC article.
Somatic 9p24.1 alterations in HPV- head and neck squamous cancer dictate immune microenvironment and anti-PD-1 checkpoint inhibitor activity.
Zhao X, Cohen EEW, William WN Jr, Bianchi JJ, Abraham JP, Magee D, Spetzler DB, Gutkind JS, Alexandrov LB, Cavenee WK, Lippman SM, Davoli T. Zhao X, et al. Proc Natl Acad Sci U S A. 2022 Nov 22;119(47):e2213835119. doi: 10.1073/pnas.2213835119. Epub 2022 Nov 17. Proc Natl Acad Sci U S A. 2022. PMID: 36395141 Free PMC article.
Spatial PD-L1, immune-cell microenvironment, and genomic copy-number alteration patterns and drivers of invasive-disease transition in prospective oral precancer cohort.
William WN Jr, Zhang J, Zhao X, Parra ER, Uraoka N, Lin HY, Peng SA, El-Naggar AK, Rodriguez-Canales J, Song J, Gillenwater AM, Wistuba II, Myers JN, Gold KA, Ferrarotto R, Hwu P, Davoli T, Lee JJ, Heymach JV, Papadimitrakopoulou VA, Lippman SM. William WN Jr, et al. Among authors: zhao x. Cancer. 2023 Mar 1;129(5):714-727. doi: 10.1002/cncr.34607. Epub 2023 Jan 3. Cancer. 2023. PMID: 36597662 Free PMC article.
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