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Page 1
Proteomic discovery of chemical probes that perturb protein complexes in human cells.
Lazear MR, Remsberg JR, Jaeger MG, Rothamel K, Her HL, DeMeester KE, Njomen E, Hogg SJ, Rahman J, Whitby LR, Won SJ, Schafroth MA, Ogasawara D, Yokoyama M, Lindsey GL, Li H, Germain J, Barbas S, Vaughan J, Hanigan TW, Vartabedian VF, Reinhardt CJ, Dix MM, Koo SJ, Heo I, Teijaro JR, Simon GM, Ghosh B, Abdel-Wahab O, Ahn K, Saghatelian A, Melillo B, Schreiber SL, Yeo GW, Cravatt BF. Lazear MR, et al. Among authors: vartabedian vf. Mol Cell. 2023 May 18;83(10):1725-1742.e12. doi: 10.1016/j.molcel.2023.03.026. Epub 2023 Apr 20. Mol Cell. 2023. PMID: 37084731 Free PMC article.
Selective blockade of the lyso-PS lipase ABHD12 stimulates immune responses in vivo.
Ogasawara D, Ichu TA, Vartabedian VF, Benthuysen J, Jing H, Reed A, Ulanovskaya OA, Hulce JJ, Roberts A, Brown S, Rosen H, Teijaro JR, Cravatt BF. Ogasawara D, et al. Among authors: vartabedian vf. Nat Chem Biol. 2018 Dec;14(12):1099-1108. doi: 10.1038/s41589-018-0155-8. Epub 2018 Nov 12. Nat Chem Biol. 2018. PMID: 30420694 Free PMC article.
Sialic Acid Ligands of CD28 Suppress Costimulation of T Cells.
Edgar LJ, Thompson AJ, Vartabedian VF, Kikuchi C, Woehl JL, Teijaro JR, Paulson JC. Edgar LJ, et al. Among authors: vartabedian vf. ACS Cent Sci. 2021 Sep 22;7(9):1508-1515. doi: 10.1021/acscentsci.1c00525. Epub 2021 Aug 23. ACS Cent Sci. 2021. PMID: 34584952 Free PMC article.
Antitumor activity of a systemic STING-activating non-nucleotide cGAMP mimetic.
Chin EN, Yu C, Vartabedian VF, Jia Y, Kumar M, Gamo AM, Vernier W, Ali SH, Kissai M, Lazar DC, Nguyen N, Pereira LE, Benish B, Woods AK, Joseph SB, Chu A, Johnson KA, Sander PN, Martínez-Peña F, Hampton EN, Young TS, Wolan DW, Chatterjee AK, Schultz PG, Petrassi HM, Teijaro JR, Lairson LL. Chin EN, et al. Among authors: vartabedian vf. Science. 2020 Aug 21;369(6506):993-999. doi: 10.1126/science.abb4255. Science. 2020. PMID: 32820126
Tumor membrane-based vaccine immunotherapy in combination with anti-CTLA-4 antibody confers protection against immune checkpoint resistant murine triple-negative breast cancer.
Pack CD, Bommireddy R, Munoz LE, Patel JM, Bozeman EN, Dey P, Radhakrishnan V, Vartabedian VF, Venkat K, Ramachandiran S, Reddy SJC, Selvaraj P. Pack CD, et al. Among authors: vartabedian vf. Hum Vaccin Immunother. 2020 Dec 1;16(12):3184-3193. doi: 10.1080/21645515.2020.1754691. Epub 2020 Jun 12. Hum Vaccin Immunother. 2020. PMID: 32530786 Free PMC article.
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