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3D genome mapping identifies subgroup-specific chromosome conformations and tumor-dependency genes in ependymoma.
Okonechnikov K, Camgöz A, Chapman O, Wani S, Park DE, Hübner JM, Chakraborty A, Pagadala M, Bump R, Chandran S, Kraft K, Acuna-Hidalgo R, Reid D, Sikkink K, Mauermann M, Juarez EF, Jenseit A, Robinson JT, Pajtler KW, Milde T, Jäger N, Fiesel P, Morgan L, Sridhar S, Coufal NG, Levy M, Malicki D, Hobbs C, Kingsmore S, Nahas S, Snuderl M, Crawford J, Wechsler-Reya RJ, Davidson TB, Cotter J, Michaiel G, Fleischhack G, Mundlos S, Schmitt A, Carter H, Michealraj KA, Kumar SA, Taylor MD, Rich J, Buchholz F, Mesirov JP, Pfister SM, Ay F, Dixon JR, Kool M, Chavez L. Okonechnikov K, et al. Among authors: buchholz f. Nat Commun. 2023 Apr 21;14(1):2300. doi: 10.1038/s41467-023-38044-0. Nat Commun. 2023. PMID: 37085539 Free PMC article.
Inactivation of Cancer Mutations Utilizing CRISPR/Cas9.
Gebler C, Lohoff T, Paszkowski-Rogacz M, Mircetic J, Chakraborty D, Camgoz A, Hamann MV, Theis M, Thiede C, Buchholz F. Gebler C, et al. Among authors: buchholz f. J Natl Cancer Inst. 2016 Aug 30;109(1):djw183. doi: 10.1093/jnci/djw183. Print 2017 Jan. J Natl Cancer Inst. 2016. PMID: 27576906 Free PMC article.
Phylointeractomics reconstructs functional evolution of protein binding.
Kappei D, Scheibe M, Paszkowski-Rogacz M, Bluhm A, Gossmann TI, Dietz S, Dejung M, Herlyn H, Buchholz F, Mann M, Butter F. Kappei D, et al. Among authors: buchholz f. Nat Commun. 2017 Feb 8;8:14334. doi: 10.1038/ncomms14334. Nat Commun. 2017. PMID: 28176777 Free PMC article.
STK3 is a therapeutic target for a subset of acute myeloid leukemias.
Camgoz A, Paszkowski-Rogacz M, Satpathy S, Wermke M, Hamann MV, von Bonin M, Choudhary C, Knapp S, Buchholz F. Camgoz A, et al. Among authors: buchholz f. Oncotarget. 2018 May 22;9(39):25458-25473. doi: 10.18632/oncotarget.25238. eCollection 2018 May 22. Oncotarget. 2018. PMID: 29876001 Free PMC article.
Correction of a Factor VIII genomic inversion with designer-recombinases.
Lansing F, Mukhametzyanova L, Rojo-Romanos T, Iwasawa K, Kimura M, Paszkowski-Rogacz M, Karpinski J, Grass T, Sonntag J, Schneider PM, Günes C, Hoersten J, Schmitt LT, Rodriguez-Muela N, Knöfler R, Takebe T, Buchholz F. Lansing F, et al. Among authors: buchholz f. Nat Commun. 2022 Jan 20;13(1):422. doi: 10.1038/s41467-022-28080-7. Nat Commun. 2022. PMID: 35058465 Free PMC article.
218 results