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The genome-wide mutational consequences of DNA hypomethylation.
Besselink N, Keijer J, Vermeulen C, Boymans S, de Ridder J, van Hoeck A, Cuppen E, Kuijk E. Besselink N, et al. Sci Rep. 2023 Apr 27;13(1):6874. doi: 10.1038/s41598-023-33932-3. Sci Rep. 2023. PMID: 37106015 Free PMC article.
Early divergence of mutational processes in human fetal tissues.
Kuijk E, Blokzijl F, Jager M, Besselink N, Boymans S, Chuva de Sousa Lopes SM, van Boxtel R, Cuppen E. Kuijk E, et al. Among authors: besselink n. Sci Adv. 2019 May 29;5(5):eaaw1271. doi: 10.1126/sciadv.aaw1271. eCollection 2019 May. Sci Adv. 2019. PMID: 31149636 Free PMC article.
5-Fluorouracil treatment induces characteristic T>G mutations in human cancer.
Christensen S, Van der Roest B, Besselink N, Janssen R, Boymans S, Martens JWM, Yaspo ML, Priestley P, Kuijk E, Cuppen E, Van Hoeck A. Christensen S, et al. Among authors: besselink n. Nat Commun. 2019 Oct 8;10(1):4571. doi: 10.1038/s41467-019-12594-8. Nat Commun. 2019. PMID: 31594944 Free PMC article.
The mutational impact of culturing human pluripotent and adult stem cells.
Kuijk E, Jager M, van der Roest B, Locati MD, Van Hoeck A, Korzelius J, Janssen R, Besselink N, Boymans S, van Boxtel R, Cuppen E. Kuijk E, et al. Among authors: besselink n. Nat Commun. 2020 May 19;11(1):2493. doi: 10.1038/s41467-020-16323-4. Nat Commun. 2020. PMID: 32427826 Free PMC article.
Precancerous liver diseases do not cause increased mutagenesis in liver stem cells.
Nguyen L, Jager M, Lieshout R, de Ruiter PE, Locati MD, Besselink N, van der Roest B, Janssen R, Boymans S, de Jonge J, IJzermans JNM, Doukas M, Verstegen MMA, van Boxtel R, van der Laan LJW, Cuppen E, Kuijk E. Nguyen L, et al. Among authors: besselink n. Commun Biol. 2021 Nov 18;4(1):1301. doi: 10.1038/s42003-021-02839-y. Commun Biol. 2021. PMID: 34795391 Free PMC article.
Genome-wide analysis of somatic noncoding mutation patterns in cancer.
Dietlein F, Wang AB, Fagre C, Tang A, Besselink NJM, Cuppen E, Li C, Sunyaev SR, Neal JT, Van Allen EM. Dietlein F, et al. Among authors: besselink njm. Science. 2022 Apr 8;376(6589):eabg5601. doi: 10.1126/science.abg5601. Epub 2022 Apr 8. Science. 2022. PMID: 35389777 Free PMC article.
34 results