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The genome-wide mutational consequences of DNA hypomethylation.
Besselink N, Keijer J, Vermeulen C, Boymans S, de Ridder J, van Hoeck A, Cuppen E, Kuijk E. Besselink N, et al. Among authors: keijer j. Sci Rep. 2023 Apr 27;13(1):6874. doi: 10.1038/s41598-023-33932-3. Sci Rep. 2023. PMID: 37106015 Free PMC article.
Mitochondrial H2O2 release does not directly cause damage to chromosomal DNA.
van Soest DMK, Polderman PE, den Toom WTF, Keijer JP, van Roosmalen MJ, Leyten TMF, Lehmann J, Zwakenberg S, De Henau S, van Boxtel R, Burgering BMT, Dansen TB. van Soest DMK, et al. Among authors: keijer jp. Nat Commun. 2024 Mar 28;15(1):2725. doi: 10.1038/s41467-024-47008-x. Nat Commun. 2024. PMID: 38548751 Free PMC article.
Translatability of mouse muscle-aging for humans: the role of sex.
de Jong JCBC, Caspers MPM, Worms N, Keijzer N, Kleemann R, Menke AL, Nieuwenhuizen AG, Keijer J, Verschuren L, van den Hoek AM. de Jong JCBC, et al. Among authors: keijer j. Geroscience. 2024 Jun;46(3):3341-3360. doi: 10.1007/s11357-024-01082-7. Epub 2024 Jan 24. Geroscience. 2024. PMID: 38265577 Free PMC article.
SIRT5 variants from patients with mitochondrial disease are associated with reduced SIRT5 stability and activity, but not with neuropathology.
Yuan T, Kumar S, Skinner M, Victor-Joseph R, Abuaita M, Keijer J, Zhang J, Kunkel TJ, Liu Y, Petrunak EM, Saunders TL, Lieberman AP, Stuckey JA, Neamati N, Al-Murshedi F, Alfadhel M, Spelbrink JN, Rodenburg R, de Boer VCJ, Lombard DB. Yuan T, et al. Among authors: keijer j. bioRxiv [Preprint]. 2023 Dec 8:2023.12.06.570371. doi: 10.1101/2023.12.06.570371. bioRxiv. 2023. PMID: 38105987 Free PMC article. Preprint.
Study protocol: Identification and validation of integrative biomarkers of physical activity level and health in children and adolescents (INTEGRActiv).
Picó C, Lurbe E, Keijer J, Kopecky J, Landrier JF, Álvarez-Pitti J, Martin JC, Oliver P, Palou A, Palou M, Zouhar P, Ribot J, Rodríguez AM, Sánchez J, Serra F, Bonet ML. Picó C, et al. Among authors: keijer j. Front Pediatr. 2023 Sep 12;11:1250731. doi: 10.3389/fped.2023.1250731. eCollection 2023. Front Pediatr. 2023. PMID: 37772038 Free PMC article. Review.
Normobaric hypoxia shows enhanced FOXO1 signaling in obese mouse gastrocnemius muscle linked to metabolism and muscle structure and neuromuscular innervation.
Song J, Duivenvoorde LPM, Grefte S, Kuda O, Martínez-Ramírez F, van der Stelt I, Mastorakou D, van Schothorst EM, Keijer J. Song J, et al. Among authors: keijer j. Pflugers Arch. 2023 Nov;475(11):1265-1281. doi: 10.1007/s00424-023-02854-4. Epub 2023 Sep 1. Pflugers Arch. 2023. PMID: 37656229 Free PMC article.
257 results