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Applications of single-cell RNA sequencing in drug discovery and development.
Van de Sande B, Lee JS, Mutasa-Gottgens E, Naughton B, Bacon W, Manning J, Wang Y, Pollard J, Mendez M, Hill J, Kumar N, Cao X, Chen X, Khaladkar M, Wen J, Leach A, Ferran E. Van de Sande B, et al. Among authors: lee js. Nat Rev Drug Discov. 2023 Jun;22(6):496-520. doi: 10.1038/s41573-023-00688-4. Epub 2023 Apr 28. Nat Rev Drug Discov. 2023. PMID: 37117846 Free PMC article. Review.
An experimental model of anti-PD-1 resistance exhibits activation of TGFß and Notch pathways and is sensitive to local mRNA immunotherapy.
Bernardo M, Tolstykh T, Zhang YA, Bangari DS, Cao H, Heyl KA, Lee JS, Malkova NV, Malley K, Marquez E, Pollard J, Qu H, Roberts E, Ryan S, Singh K, Sun F, Wang E, Bahjat K, Wiederschain D, Wagenaar TR. Bernardo M, et al. Among authors: lee js. Oncoimmunology. 2021 Mar 16;10(1):1881268. doi: 10.1080/2162402X.2021.1881268. Oncoimmunology. 2021. PMID: 33796402 Free PMC article.
SAR439859, a Novel Selective Estrogen Receptor Degrader (SERD), Demonstrates Effective and Broad Antitumor Activity in Wild-Type and Mutant ER-Positive Breast Cancer Models.
Shomali M, Cheng J, Sun F, Koundinya M, Guo Z, Hebert AT, McManus J, Levit MN, Hoffmann D, Courjaud A, Arrebola R, Cao H, Pollard J, Lee JS, Besret L, Caron A, Bangari DS, Abecassis PY, Schio L, El-Ahmad Y, Halley F, Tabart M, Certal V, Thompson F, McCort G, Filoche-Rommé B, Cheng H, Garcia-Echeverria C, Debussche L, Bouaboula M. Shomali M, et al. Among authors: lee js. Mol Cancer Ther. 2021 Feb;20(2):250-262. doi: 10.1158/1535-7163.MCT-20-0390. Epub 2020 Dec 11. Mol Cancer Ther. 2021. PMID: 33310762
AMEERA-1 phase 1/2 study of amcenestrant, SAR439859, in postmenopausal women with ER-positive/HER2-negative advanced breast cancer.
Bardia A, Chandarlapaty S, Linden HM, Ulaner GA, Gosselin A, Cartot-Cotton S, Cohen P, Doroumian S, Paux G, Celanovic M, Pelekanou V, Ming JE, Ternès N, Bouaboula M, Lee JS, Bauchet AL, Campone M. Bardia A, et al. Among authors: lee js. Nat Commun. 2022 Jul 15;13(1):4116. doi: 10.1038/s41467-022-31668-8. Nat Commun. 2022. PMID: 35840573 Free PMC article. Clinical Trial.
Antigenic Characterization of Circulating and Emerging SARS-CoV-2 Variants in the U.S. throughout the Delta to Omicron Waves.
Di H, Pusch EA, Jones J, Kovacs NA, Hassell N, Sheth M, Lynn KS, Keller MW, Wilson MM, Keong LM, Cui D, Park SH, Chau R, Lacek KA, Liddell JD, Kirby MK, Yang G, Johnson M, Thor S, Zanders N, Feng C, Surie D, DeCuir J, Lester SN, Atherton L, Hicks H, Tamin A, Harcourt JL, Coughlin MM, Self WH, Rhoads JP, Gibbs KW, Hager DN, Shapiro NI, Exline MC, Lauring AS, Rambo-Martin B, Paden CR, Kondor RJ, Lee JS, Barnes JR, Thornburg NJ, Zhou B, Wentworth DE, Davis CT. Di H, et al. Among authors: lee js. Vaccines (Basel). 2024 May 7;12(5):505. doi: 10.3390/vaccines12050505. Vaccines (Basel). 2024. PMID: 38793756
Oral Health-Related Quality of Life in Rare Disorders of Congenital Facial Weakness.
Liberton DK, Almpani K, Mishra R, Bassim C, Van Ryzin C, On Behalf Of The Moebius Syndrome Research Consortium, Webb BD, Jabs EW, Engle EC, Collins FS, Manoli I, Lee JS. Liberton DK, et al. Among authors: lee js. Int J Environ Res Public Health. 2024 May 13;21(5):615. doi: 10.3390/ijerph21050615. Int J Environ Res Public Health. 2024. PMID: 38791829
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