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Applications of single-cell RNA sequencing in drug discovery and development.
Van de Sande B, Lee JS, Mutasa-Gottgens E, Naughton B, Bacon W, Manning J, Wang Y, Pollard J, Mendez M, Hill J, Kumar N, Cao X, Chen X, Khaladkar M, Wen J, Leach A, Ferran E. Van de Sande B, et al. Nat Rev Drug Discov. 2023 Jun;22(6):496-520. doi: 10.1038/s41573-023-00688-4. Epub 2023 Apr 28. Nat Rev Drug Discov. 2023. PMID: 37117846 Free PMC article. Review.
A scalable SCENIC workflow for single-cell gene regulatory network analysis.
Van de Sande B, Flerin C, Davie K, De Waegeneer M, Hulselmans G, Aibar S, Seurinck R, Saelens W, Cannoodt R, Rouchon Q, Verbeiren T, De Maeyer D, Reumers J, Saeys Y, Aerts S. Van de Sande B, et al. Nat Protoc. 2020 Jul;15(7):2247-2276. doi: 10.1038/s41596-020-0336-2. Epub 2020 Jun 19. Nat Protoc. 2020. PMID: 32561888
iRegulon: from a gene list to a gene regulatory network using large motif and track collections.
Janky R, Verfaillie A, Imrichová H, Van de Sande B, Standaert L, Christiaens V, Hulselmans G, Herten K, Naval Sanchez M, Potier D, Svetlichnyy D, Kalender Atak Z, Fiers M, Marine JC, Aerts S. Janky R, et al. Among authors: van de sande b. PLoS Comput Biol. 2014 Jul 24;10(7):e1003731. doi: 10.1371/journal.pcbi.1003731. eCollection 2014 Jul. PLoS Comput Biol. 2014. PMID: 25058159 Free PMC article.
Adult interfollicular tumour-initiating cells are reprogrammed into an embryonic hair follicle progenitor-like fate during basal cell carcinoma initiation.
Youssef KK, Lapouge G, Bouvrée K, Rorive S, Brohée S, Appelstein O, Larsimont JC, Sukumaran V, Van de Sande B, Pucci D, Dekoninck S, Berthe JV, Aerts S, Salmon I, del Marmol V, Blanpain C. Youssef KK, et al. Among authors: van de sande b. Nat Cell Biol. 2012 Dec;14(12):1282-94. doi: 10.1038/ncb2628. Epub 2012 Nov 25. Nat Cell Biol. 2012. PMID: 23178882
Binaural and cochlear disparities.
Joris PX, Van de Sande B, Louage DH, van der Heijden M. Joris PX, et al. Among authors: van de sande b. Proc Natl Acad Sci U S A. 2006 Aug 22;103(34):12917-22. doi: 10.1073/pnas.0601396103. Epub 2006 Aug 14. Proc Natl Acad Sci U S A. 2006. PMID: 16908859 Free PMC article.
18 results