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Therapeutic blocking of VEGF binding to neuropilin-2 diminishes PD-L1 expression to activate antitumor immunity in prostate cancer.
Wang M, Wisniewski CA, Xiong C, Chhoy P, Goel HL, Kumar A, Zhu LJ, Li R, St Louis PA, Ferreira LM, Pakula H, Xu Z, Loda M, Jiang Z, Brehm MA, Mercurio AM. Wang M, et al. Among authors: loda m. Sci Transl Med. 2023 May 3;15(694):eade5855. doi: 10.1126/scitranslmed.ade5855. Epub 2023 May 3. Sci Transl Med. 2023. PMID: 37134151
CREB5 Promotes Resistance to Androgen-Receptor Antagonists and Androgen Deprivation in Prostate Cancer.
Hwang JH, Seo JH, Beshiri ML, Wankowicz S, Liu D, Cheung A, Li J, Qiu X, Hong AL, Botta G, Golumb L, Richter C, So J, Sandoval GJ, Giacomelli AO, Ly SH, Han C, Dai C, Pakula H, Sheahan A, Piccioni F, Gjoerup O, Loda M, Sowalsky AG, Ellis L, Long H, Root DE, Kelly K, Van Allen EM, Freedman ML, Choudhury AD, Hahn WC. Hwang JH, et al. Among authors: loda m. Cell Rep. 2019 Nov 19;29(8):2355-2370.e6. doi: 10.1016/j.celrep.2019.10.068. Cell Rep. 2019. PMID: 31747605 Free PMC article.
Temporal evolution of cellular heterogeneity during the progression to advanced AR-negative prostate cancer.
Brady NJ, Bagadion AM, Singh R, Conteduca V, Van Emmenis L, Arceci E, Pakula H, Carelli R, Khani F, Bakht M, Sigouros M, Bareja R, Sboner A, Elemento O, Tagawa S, Nanus DM, Loda M, Beltran H, Robinson B, Rickman DS. Brady NJ, et al. Among authors: loda m. Nat Commun. 2021 Jun 7;12(1):3372. doi: 10.1038/s41467-021-23780-y. Nat Commun. 2021. PMID: 34099734 Free PMC article.
"Stromal cells in prostate cancer pathobiology: friends or foes?".
Pederzoli F, Raffo M, Pakula H, Ravera F, Nuzzo PV, Loda M. Pederzoli F, et al. Among authors: loda m. Br J Cancer. 2023 Apr;128(6):930-939. doi: 10.1038/s41416-022-02085-x. Epub 2022 Dec 8. Br J Cancer. 2023. PMID: 36482187 Free PMC article. Review.
Adipose Triglyceride Lipase Is a Therapeutic Target in Advanced Prostate Cancer That Promotes Metabolic Plasticity.
Awad D, Cao PHA, Pulliam TL, Spradlin M, Subramani E, Tellman TV, Ribeiro CF, Muzzioli R, Jewell BE, Pakula H, Ackroyd JJ, Murray MM, Han JJ, Leng M, Jain A, Piyarathna B, Liu J, Song X, Zhang J, Klekers AR, Drake JM, Ittmann MM, Coarfa C, Piwnica-Worms D, Farach-Carson MC, Loda M, Eberlin LS, Frigo DE. Awad D, et al. Among authors: loda m. Cancer Res. 2024 Mar 4;84(5):703-724. doi: 10.1158/0008-5472.CAN-23-0555. Cancer Res. 2024. PMID: 38038968
Distinct mesenchymal cell states mediate prostate cancer progression.
Pakula H, Omar M, Carelli R, Pederzoli F, Fanelli GN, Pannellini T, Socciarelli F, Van Emmenis L, Rodrigues S, Fidalgo-Ribeiro C, Nuzzo PV, Brady NJ, Dinalankara W, Jere M, Valencia I, Saladino C, Stone J, Unkenholz C, Garner R, Alexanderani MK, Khani F, de Almeida FN, Abate-Shen C, Greenblatt MB, Rickman DS, Barbieri CE, Robinson BD, Marchionni L, Loda M. Pakula H, et al. Among authors: loda m. Nat Commun. 2024 Jan 8;15(1):363. doi: 10.1038/s41467-023-44210-1. Nat Commun. 2024. PMID: 38191471 Free PMC article.
494 results