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Identification of biomarkers for glycaemic deterioration in type 2 diabetes.
Slieker RC, Donnelly LA, Akalestou E, Lopez-Noriega L, Melhem R, Güneş A, Abou Azar F, Efanov A, Georgiadou E, Muniangi-Muhitu H, Sheikh M, Giordano GN, Åkerlund M, Ahlqvist E, Ali A, Banasik K, Brunak S, Barovic M, Bouland GA, Burdet F, Canouil M, Dragan I, Elders PJM, Fernandez C, Festa A, Fitipaldi H, Froguel P, Gudmundsdottir V, Gudnason V, Gerl MJ, van der Heijden AA, Jennings LL, Hansen MK, Kim M, Leclerc I, Klose C, Kuznetsov D, Mansour Aly D, Mehl F, Marek D, Melander O, Niknejad A, Ottosson F, Pavo I, Duffin K, Syed SK, Shaw JL, Cabrera O, Pullen TJ, Simons K, Solimena M, Suvitaival T, Wretlind A, Rossing P, Lyssenko V, Legido Quigley C, Groop L, Thorens B, Franks PW, Lim GE, Estall J, Ibberson M, Beulens JWJ, 't Hart LM, Pearson ER, Rutter GA. Slieker RC, et al. Among authors: gudmundsdottir v. Nat Commun. 2023 May 3;14(1):2533. doi: 10.1038/s41467-023-38148-7. Nat Commun. 2023. PMID: 37137910 Free PMC article.
Metabolite ratios as potential biomarkers for type 2 diabetes: a DIRECT study.
Molnos S, Wahl S, Haid M, Eekhoff EMW, Pool R, Floegel A, Deelen J, Much D, Prehn C, Breier M, Draisma HH, van Leeuwen N, Simonis-Bik AMC, Jonsson A, Willemsen G, Bernigau W, Wang-Sattler R, Suhre K, Peters A, Thorand B, Herder C, Rathmann W, Roden M, Gieger C, Kramer MHH, van Heemst D, Pedersen HK, Gudmundsdottir V, Schulze MB, Pischon T, de Geus EJC, Boeing H, Boomsma DI, Ziegler AG, Slagboom PE, Hummel S, Beekman M, Grallert H, Brunak S, McCarthy MI, Gupta R, Pearson ER, Adamski J, 't Hart LM. Molnos S, et al. Among authors: gudmundsdottir v. Diabetologia. 2018 Jan;61(1):117-129. doi: 10.1007/s00125-017-4436-7. Epub 2017 Oct 25. Diabetologia. 2018. PMID: 28936587 Free PMC article.
Integrative network analysis highlights biological processes underlying GLP-1 stimulated insulin secretion: A DIRECT study.
Gudmundsdottir V, Pedersen HK, Allebrandt KV, Brorsson C, van Leeuwen N, Banasik K, Mahajan A, Groves CJ, van de Bunt M, Dawed AY, Fritsche A, Staiger H, Simonis-Bik AMC, Deelen J, Kramer MHH, Dietrich A, Hübschle T, Willemsen G, Häring HU, de Geus EJC, Boomsma DI, Eekhoff EMW, Ferrer J, McCarthy MI, Pearson ER, Gupta R, Brunak S, 't Hart LM. Gudmundsdottir V, et al. PLoS One. 2018 Jan 2;13(1):e0189886. doi: 10.1371/journal.pone.0189886. eCollection 2018. PLoS One. 2018. PMID: 29293525 Free PMC article.
A computational framework to integrate high-throughput '-omics' datasets for the identification of potential mechanistic links.
Pedersen HK, Forslund SK, Gudmundsdottir V, Petersen AØ, Hildebrand F, Hyötyläinen T, Nielsen T, Hansen T, Bork P, Ehrlich SD, Brunak S, Oresic M, Pedersen O, Nielsen HB. Pedersen HK, et al. Among authors: gudmundsdottir v. Nat Protoc. 2018 Dec;13(12):2781-2800. doi: 10.1038/s41596-018-0064-z. Nat Protoc. 2018. PMID: 30382244
Genetic studies of abdominal MRI data identify genes regulating hepcidin as major determinants of liver iron concentration.
Wilman HR, Parisinos CA, Atabaki-Pasdar N, Kelly M, Thomas EL, Neubauer S; IMI DIRECT Consortium; Mahajan A, Hingorani AD, Patel RS, Hemingway H, Franks PW, Bell JD, Banerjee R, Yaghootkar H. Wilman HR, et al. J Hepatol. 2019 Sep;71(3):594-602. doi: 10.1016/j.jhep.2019.05.032. Epub 2019 Jun 19. J Hepatol. 2019. PMID: 31226389 Free PMC article.
Circulating Protein Signatures and Causal Candidates for Type 2 Diabetes.
Gudmundsdottir V, Zaghlool SB, Emilsson V, Aspelund T, Ilkov M, Gudmundsson EF, Jonsson SM, Zilhão NR, Lamb JR, Suhre K, Jennings LL, Gudnason V. Gudmundsdottir V, et al. Diabetes. 2020 Aug;69(8):1843-1853. doi: 10.2337/db19-1070. Epub 2020 May 8. Diabetes. 2020. PMID: 32385057 Free PMC article.
It's in Our Blood: A Glimpse of Personalized Medicine.
Lamb JR, Jennings LL, Gudmundsdottir V, Gudnason V, Emilsson V. Lamb JR, et al. Among authors: gudmundsdottir v. Trends Mol Med. 2021 Jan;27(1):20-30. doi: 10.1016/j.molmed.2020.09.003. Epub 2020 Sep 25. Trends Mol Med. 2021. PMID: 32988739 Free PMC article. Review.
61 results