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Plasma membrane preassociation drives β-arrestin coupling to receptors and activation.
Grimes J, Koszegi Z, Lanoiselée Y, Miljus T, O'Brien SL, Stepniewski TM, Medel-Lacruz B, Baidya M, Makarova M, Mistry R, Goulding J, Drube J, Hoffmann C, Owen DM, Shukla AK, Selent J, Hill SJ, Calebiro D. Grimes J, et al. Among authors: shukla ak. Cell. 2023 May 11;186(10):2238-2255.e20. doi: 10.1016/j.cell.2023.04.018. Epub 2023 May 4. Cell. 2023. PMID: 37146613 Free PMC article.
SnapShot: GPCR-Ligand Interactions.
Ghosh E, Nidhi K, Shukla AK. Ghosh E, et al. Among authors: shukla ak. Cell. 2014 Dec 18;159(7):1712, 1712.e1. doi: 10.1016/j.cell.2014.12.008. Cell. 2014. PMID: 25525884 Free article.
GPCR-G Protein-β-Arrestin Super-Complex Mediates Sustained G Protein Signaling.
Thomsen ARB, Plouffe B, Cahill TJ 3rd, Shukla AK, Tarrasch JT, Dosey AM, Kahsai AW, Strachan RT, Pani B, Mahoney JP, Huang L, Breton B, Heydenreich FM, Sunahara RK, Skiniotis G, Bouvier M, Lefkowitz RJ. Thomsen ARB, et al. Among authors: shukla ak. Cell. 2016 Aug 11;166(4):907-919. doi: 10.1016/j.cell.2016.07.004. Epub 2016 Aug 4. Cell. 2016. PMID: 27499021 Free PMC article.
A synthetic intrabody-based selective and generic inhibitor of GPCR endocytosis.
Ghosh E, Srivastava A, Baidya M, Kumari P, Dwivedi H, Nidhi K, Ranjan R, Dogra S, Koide A, Yadav PN, Sidhu SS, Koide S, Shukla AK. Ghosh E, et al. Among authors: shukla ak. Nat Nanotechnol. 2017 Dec;12(12):1190-1198. doi: 10.1038/nnano.2017.188. Epub 2017 Oct 2. Nat Nanotechnol. 2017. PMID: 28967893 Free PMC article.
GPCR Signaling: The Interplay of Gαi and β-arrestin.
Dwivedi H, Baidya M, Shukla AK. Dwivedi H, et al. Among authors: shukla ak. Curr Biol. 2018 Apr 2;28(7):R324-R327. doi: 10.1016/j.cub.2018.02.027. Curr Biol. 2018. PMID: 29614294 Free article.
533 results