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A strategy for high antibody expression with low anti-drug antibodies using AAV9 vectors.
Davis-Gardner ME, Weber JA, Xie J, Pekrun K, Alexander EA, Weisgrau KL, Furlott JR, Rakasz EG, Kay MA, Gao G, Farzan M, Gardner MR. Davis-Gardner ME, et al. Among authors: farzan m. Front Immunol. 2023 Apr 21;14:1105617. doi: 10.3389/fimmu.2023.1105617. eCollection 2023. Front Immunol. 2023. PMID: 37153616 Free PMC article.
High throughput screening for drugs that inhibit 3C-like protease in SARS-CoV-2.
Smith E, Davis-Gardner ME, Garcia-Ordonez RD, Nguyen TT, Hull M, Chen E, Yu X, Bannister TD, Baillargeon P, Scampavia L, Griffin P, Farzan M, Spicer TP. Smith E, et al. Among authors: farzan m. SLAS Discov. 2023 Apr;28(3):95-101. doi: 10.1016/j.slasd.2023.01.001. Epub 2023 Jan 14. SLAS Discov. 2023. PMID: 36646172 Free PMC article.
A lentiviral vector B cell gene therapy platform for the delivery of the anti-HIV-1 eCD4-Ig-knob-in-hole-reversed immunoadhesin.
Vamva E, Ozog S, Leaman DP, Yu-Hong Cheng R, Irons NJ, Ott A, Stoffers C, Khan I, Goebrecht GKE, Gardner MR, Farzan M, Rawlings DJ, Zwick MB, James RG, Torbett BE. Vamva E, et al. Among authors: farzan m. Mol Ther Methods Clin Dev. 2023 Feb 11;28:366-384. doi: 10.1016/j.omtm.2023.02.004. eCollection 2023 Mar 9. Mol Ther Methods Clin Dev. 2023. PMID: 36879849 Free PMC article.
Highlights from the Tenth International Workshop on HIV Persistence during Therapy, December 13-16, 2022, Miami, Florida-USA.
Archin N, Bar KJ, Burdo T, Caskey M, Chahroudi A, Farzan M, Ho YC, Jones RB, Kearney M, Kuritzkes D, Margolis D, Martinez-Picado J, Okoye A, Salgado M, Stevenson M. Archin N, et al. Among authors: farzan m. J Virus Erad. 2023 Jan 27;9(1):100315. doi: 10.1016/j.jve.2023.100315. eCollection 2023 Mar. J Virus Erad. 2023. PMID: 36911658 Free PMC article.
An IgM-like inhalable ACE2 fusion protein broadly neutralizes SARS-CoV-2 variants.
Liu J, Mao F, Chen J, Lu S, Qi Y, Sun Y, Fang L, Yeung ML, Liu C, Yu G, Li G, Liu X, Yao Y, Huang P, Hao D, Liu Z, Ding Y, Liu H, Yang F, Chen P, Sa R, Sheng Y, Tian X, Peng R, Li X, Luo J, Cheng Y, Zheng Y, Lin Y, Song R, Jin R, Huang B, Choe H, Farzan M, Yuen KY, Tan W, Peng X, Sui J, Li W. Liu J, et al. Among authors: farzan m. Nat Commun. 2023 Aug 25;14(1):5191. doi: 10.1038/s41467-023-40933-3. Nat Commun. 2023. PMID: 37626079 Free PMC article.
In vivo affinity maturation of the HIV-1 Env-binding domain of CD4.
Pan A, Bailey CC, Ou T, Xu J, Liu X, Hu B, Crynen G, Skamangas N, Bronkema N, Tran M, Mu H, Zhang X, Yin Y, Alpert MD, He W, Farzan M. Pan A, et al. Among authors: farzan m. Res Sq [Preprint]. 2024 Feb 9:rs.3.rs-3922904. doi: 10.21203/rs.3.rs-3922904/v1. Res Sq. 2024. PMID: 38405717 Free PMC article. Preprint.
In vivo affinity maturation of the HIV-1 Env-binding domain of CD4.
Pan A, Bailey CC, Ou T, Xu J, Liu X, Hu B, Crynen G, Skamangas N, Bronkema N, Tran M, Mu H, Zhang X, Yin Y, Alpert MD, He W, Farzan M. Pan A, et al. Among authors: farzan m. bioRxiv [Preprint]. 2024 Feb 5:2024.02.03.578630. doi: 10.1101/2024.02.03.578630. bioRxiv. 2024. PMID: 38370774 Free PMC article. Preprint.
219 results