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A strategy for high antibody expression with low anti-drug antibodies using AAV9 vectors.
Davis-Gardner ME, Weber JA, Xie J, Pekrun K, Alexander EA, Weisgrau KL, Furlott JR, Rakasz EG, Kay MA, Gao G, Farzan M, Gardner MR. Davis-Gardner ME, et al. Among authors: weber ja. Front Immunol. 2023 Apr 21;14:1105617. doi: 10.3389/fimmu.2023.1105617. eCollection 2023. Front Immunol. 2023. PMID: 37153616 Free PMC article.
Anti-drug Antibody Responses Impair Prophylaxis Mediated by AAV-Delivered HIV-1 Broadly Neutralizing Antibodies.
Gardner MR, Fetzer I, Kattenhorn LM, Davis-Gardner ME, Zhou AS, Alfant B, Weber JA, Kondur HR, Martinez-Navio JM, Fuchs SP, Desrosiers RC, Gao G, Lifson JD, Farzan M. Gardner MR, et al. Among authors: weber ja. Mol Ther. 2019 Mar 6;27(3):650-660. doi: 10.1016/j.ymthe.2019.01.004. Epub 2019 Jan 12. Mol Ther. 2019. PMID: 30704961 Free PMC article.
AAV-delivered eCD4-Ig protects rhesus macaques from high-dose SIVmac239 challenges.
Gardner MR, Fellinger CH, Kattenhorn LM, Davis-Gardner ME, Weber JA, Alfant B, Zhou AS, Prasad NR, Kondur HR, Newton WA, Weisgrau KL, Rakasz EG, Lifson JD, Gao G, Schultz-Darken N, Farzan M. Gardner MR, et al. Among authors: weber ja. Sci Transl Med. 2019 Jul 24;11(502):eaau5409. doi: 10.1126/scitranslmed.aau5409. Sci Transl Med. 2019. PMID: 31341061 Free PMC article.
eCD4-Ig Variants That More Potently Neutralize HIV-1.
Fetzer I, Gardner MR, Davis-Gardner ME, Prasad NR, Alfant B, Weber JA, Farzan M. Fetzer I, et al. Among authors: weber ja. J Virol. 2018 May 29;92(12):e02011-17. doi: 10.1128/JVI.02011-17. Print 2018 Jun 15. J Virol. 2018. PMID: 29593050 Free PMC article.
A Coreceptor-Mimetic Peptide Enhances the Potency of V3-Glycan Antibodies.
Fetzer I, Davis-Gardner ME, Gardner MR, Alfant B, Weber JA, Prasad NR, Zhou AS, Farzan M. Fetzer I, et al. Among authors: weber ja. J Virol. 2019 Feb 19;93(5):e01653-18. doi: 10.1128/JVI.01653-18. Print 2019 Mar 1. J Virol. 2019. PMID: 30541842 Free PMC article.
141 results