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Large libraries of single-chain trimer peptide-MHCs enable antigen-specific CD8+ T cell discovery and analysis.
Chour W, Choi J, Xie J, Chaffee ME, Schmitt TM, Finton K, DeLucia DC, Xu AM, Su Y, Chen DG, Zhang R, Yuan D, Hong S, Ng AHC, Butler JZ, Edmark RA, Jones LC, Murray KM, Peng S, Li G, Strong RK, Lee JK, Goldman JD, Greenberg PD, Heath JR. Chour W, et al. Among authors: greenberg pd. Commun Biol. 2023 May 16;6(1):528. doi: 10.1038/s42003-023-04899-8. Commun Biol. 2023. PMID: 37193826 Free PMC article.
T cell receptor gene therapy for cancer.
Schmitt TM, Ragnarsson GB, Greenberg PD. Schmitt TM, et al. Among authors: greenberg pd. Hum Gene Ther. 2009 Nov;20(11):1240-8. doi: 10.1089/hum.2009.146. Hum Gene Ther. 2009. PMID: 19702439 Free PMC article. Review.
Cyclin-A1 represents a new immunogenic targetable antigen expressed in acute myeloid leukemia stem cells with characteristics of a cancer-testis antigen.
Ochsenreither S, Majeti R, Schmitt T, Stirewalt D, Keilholz U, Loeb KR, Wood B, Choi YE, Bleakley M, Warren EH, Hudecek M, Akatsuka Y, Weissman IL, Greenberg PD. Ochsenreither S, et al. Among authors: greenberg pd. Blood. 2012 Jun 7;119(23):5492-501. doi: 10.1182/blood-2011-07-365890. Epub 2012 Apr 23. Blood. 2012. PMID: 22529286 Free PMC article.
Abrogation of SRC homology region 2 domain-containing phosphatase 1 in tumor-specific T cells improves efficacy of adoptive immunotherapy by enhancing the effector function and accumulation of short-lived effector T cells in vivo.
Stromnes IM, Fowler C, Casamina CC, Georgopolos CM, McAfee MS, Schmitt TM, Tan X, Kim TD, Choi I, Blattman JN, Greenberg PD. Stromnes IM, et al. Among authors: greenberg pd. J Immunol. 2012 Aug 15;189(4):1812-25. doi: 10.4049/jimmunol.1200552. Epub 2012 Jul 13. J Immunol. 2012. PMID: 22798667 Free PMC article.
Transferred WT1-reactive CD8+ T cells can mediate antileukemic activity and persist in post-transplant patients.
Chapuis AG, Ragnarsson GB, Nguyen HN, Chaney CN, Pufnock JS, Schmitt TM, Duerkopp N, Roberts IM, Pogosov GL, Ho WY, Ochsenreither S, Wölfl M, Bar M, Radich JP, Yee C, Greenberg PD. Chapuis AG, et al. Among authors: greenberg pd. Sci Transl Med. 2013 Feb 27;5(174):174ra27. doi: 10.1126/scitranslmed.3004916. Sci Transl Med. 2013. PMID: 23447018 Free PMC article.
281 results