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Large libraries of single-chain trimer peptide-MHCs enable antigen-specific CD8+ T cell discovery and analysis.
Chour W, Choi J, Xie J, Chaffee ME, Schmitt TM, Finton K, DeLucia DC, Xu AM, Su Y, Chen DG, Zhang R, Yuan D, Hong S, Ng AHC, Butler JZ, Edmark RA, Jones LC, Murray KM, Peng S, Li G, Strong RK, Lee JK, Goldman JD, Greenberg PD, Heath JR. Chour W, et al. Among authors: li g. Commun Biol. 2023 May 16;6(1):528. doi: 10.1038/s42003-023-04899-8. Commun Biol. 2023. PMID: 37193826 Free PMC article.
T cell antigen discovery via trogocytosis.
Li G, Bethune MT, Wong S, Joglekar AV, Leonard MT, Wang JK, Kim JT, Cheng D, Peng S, Zaretsky JM, Su Y, Luo Y, Heath JR, Ribas A, Witte ON, Baltimore D. Li G, et al. Nat Methods. 2019 Feb;16(2):183-190. doi: 10.1038/s41592-018-0305-7. Epub 2019 Jan 28. Nat Methods. 2019. PMID: 30700903 Free PMC article.
Multi-omic single-cell snapshots reveal multiple independent trajectories to drug tolerance in a melanoma cell line.
Su Y, Ko ME, Cheng H, Zhu R, Xue M, Wang J, Lee JW, Frankiw L, Xu A, Wong S, Robert L, Takata K, Yuan D, Lu Y, Huang S, Ribas A, Levine R, Nolan GP, Wei W, Plevritis SK, Li G, Baltimore D, Heath JR. Su Y, et al. Among authors: li g. Nat Commun. 2020 May 11;11(1):2345. doi: 10.1038/s41467-020-15956-9. Nat Commun. 2020. PMID: 32393797 Free PMC article.
T cell antigen discovery.
Joglekar AV, Li G. Joglekar AV, et al. Among authors: li g. Nat Methods. 2021 Aug;18(8):873-880. doi: 10.1038/s41592-020-0867-z. Epub 2020 Jul 6. Nat Methods. 2021. PMID: 32632239 Review.
Large libraries of single-chain trimer peptide-MHCs enable rapid antigen-specific CD8+ T cell discovery and analysis.
Heath J, Chour W, Choi J, Xie J, Chaffee M, Schmitt T, Finton K, Delucia D, Xu A, Su Y, Chen D, Zhang R, Yuan D, Hong S, Ng A, Butler J, Edmark R, Jones L, Murray K, Peng S, Li G, Strong R, Lee J, Goldman J, Greenberg P. Heath J, et al. Among authors: li g. Res Sq [Preprint]. 2022 Nov 18:rs.3.rs-1090664. doi: 10.21203/rs.3.rs-1090664/v1. Res Sq. 2022. PMID: 36415462 Free PMC article. Updated. Preprint.
TCR Ligand Discovery via T-Scan.
Wang Z, Cheng G, Li G. Wang Z, et al. Among authors: li g. Trends Immunol. 2019 Dec;40(12):1075-1077. doi: 10.1016/j.it.2019.10.003. Epub 2019 Nov 5. Trends Immunol. 2019. PMID: 31699586
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