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Large libraries of single-chain trimer peptide-MHCs enable antigen-specific CD8+ T cell discovery and analysis.
Chour W, Choi J, Xie J, Chaffee ME, Schmitt TM, Finton K, DeLucia DC, Xu AM, Su Y, Chen DG, Zhang R, Yuan D, Hong S, Ng AHC, Butler JZ, Edmark RA, Jones LC, Murray KM, Peng S, Li G, Strong RK, Lee JK, Goldman JD, Greenberg PD, Heath JR. Chour W, et al. Among authors: schmitt tm. Commun Biol. 2023 May 16;6(1):528. doi: 10.1038/s42003-023-04899-8. Commun Biol. 2023. PMID: 37193826 Free PMC article.
T cell receptor gene therapy for cancer.
Schmitt TM, Ragnarsson GB, Greenberg PD. Schmitt TM, et al. Hum Gene Ther. 2009 Nov;20(11):1240-8. doi: 10.1089/hum.2009.146. Hum Gene Ther. 2009. PMID: 19702439 Free PMC article. Review.
Targeting an alternate Wilms' tumor antigen 1 peptide bypasses immunoproteasome dependency.
Lahman MC, Schmitt TM, Paulson KG, Vigneron N, Buenrostro D, Wagener FD, Voillet V, Martin L, Gottardo R, Bielas J, McElrath JM, Stirewalt DL, Pogosova-Agadjanyan EL, Yeung CC, Pierce RH, Egan DN, Bar M, Hendrie PC, Kinsella S, Vakil A, Butler J, Chaffee M, Linton J, McAfee MS, Hunter DS, Bleakley M, Rongvaux A, Van den Eynde BJ, Chapuis AG, Greenberg PD. Lahman MC, et al. Among authors: schmitt tm. Sci Transl Med. 2022 Feb 9;14(631):eabg8070. doi: 10.1126/scitranslmed.abg8070. Epub 2022 Feb 9. Sci Transl Med. 2022. PMID: 35138909 Free PMC article.
Cyclin-A1 represents a new immunogenic targetable antigen expressed in acute myeloid leukemia stem cells with characteristics of a cancer-testis antigen.
Ochsenreither S, Majeti R, Schmitt T, Stirewalt D, Keilholz U, Loeb KR, Wood B, Choi YE, Bleakley M, Warren EH, Hudecek M, Akatsuka Y, Weissman IL, Greenberg PD. Ochsenreither S, et al. Blood. 2012 Jun 7;119(23):5492-501. doi: 10.1182/blood-2011-07-365890. Epub 2012 Apr 23. Blood. 2012. PMID: 22529286 Free PMC article.
83 results