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Excess dietary sodium partially restores salt and water homeostasis caused by loss of the endoplasmic reticulum molecular chaperone, GRP170, in the mouse nephron.
Porter A, Vorndran HE, Marciszyn A, Mutchler SM, Subramanya AR, Kleyman TR, Hendershot LM, Brodsky JL, Buck TM. Porter A, et al. Among authors: brodsky jl. bioRxiv [Preprint]. 2024 Jan 14:2024.01.13.575426. doi: 10.1101/2024.01.13.575426. bioRxiv. 2024. PMID: 38260467 Free PMC article. Preprint.
Loss of Grp170 results in catastrophic disruption of endoplasmic reticulum functions.
Mann MJ, Melendez-Suchi C, Sukhoplyasova M, Flory AR, Carson Irvine M, Iyer AR, Vorndran H, Guerriero CJ, Brodsky JL, Hendershot LM, Buck TM. Mann MJ, et al. Among authors: brodsky jl. bioRxiv [Preprint]. 2023 Oct 20:2023.10.19.563191. doi: 10.1101/2023.10.19.563191. bioRxiv. 2023. PMID: 37905119 Free PMC article. Updated. Preprint.
Optimization of the fluorogen-activating protein tag for quantitative protein trafficking and co-localization studies in S. cerevisiae.
Oppenheimer KG, Hager NA, McAtee CK, Filiztekin E, Shang C, Warnick JA, Bruchez MP, Brodsky JL, Prosser DC, Kwiatkowski AV, O'Donnell AF. Oppenheimer KG, et al. Among authors: brodsky jl. bioRxiv [Preprint]. 2024 May 23:2024.04.20.590399. doi: 10.1101/2024.04.20.590399. bioRxiv. 2024. PMID: 38712197 Free PMC article. Preprint.
FITM2 deficiency results in ER lipid accumulation, ER stress, reduced apolipoprotein B lipidation, and VLDL triglyceride secretion in vitro and in mouse liver.
Wang H, Nikain C, Amengual J, La Forest M, Yu Y, Wang MC, Watts R, Lehner R, Qiu Y, Cai M, Kurland IJ, Goldberg IJ, Rajan S, Hussain MM, Brodsky JL, Fisher EA. Wang H, et al. Among authors: brodsky jl. bioRxiv [Preprint]. 2023 Dec 7:2023.12.05.570183. doi: 10.1101/2023.12.05.570183. bioRxiv. 2023. PMID: 38106013 Free PMC article. Preprint.
J-domain proteins: From molecular mechanisms to diseases.
Marszalek J, De Los Rios P, Cyr D, Mayer MP, Adupa V, Andréasson C, Blatch GL, Braun JEA, Brodsky JL, Bukau B, Chapple JP, Conz C, Dementin S, Genevaux P, Genest O, Goloubinoff P, Gestwicki J, Hammond CM, Hines JK, Ishikawa K, Joachimiak LA, Kirstein J, Liberek K, Mokranjac D, Nillegoda N, Ramos CHI, Rebeaud M, Ron D, Rospert S, Sahi C, Shalgi R, Tomiczek B, Ushioda R, Ustyantseva E, Ye Y, Zylicz M, Kampinga HH. Marszalek J, et al. Among authors: brodsky jl. Cell Stress Chaperones. 2024 Feb;29(1):21-33. doi: 10.1016/j.cstres.2023.12.002. Epub 2023 Dec 23. Cell Stress Chaperones. 2024. PMID: 38320449 Free PMC article.
281 results