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Metformin reduces the clonal fitness of Dnmt3aR878H hematopoietic stem and progenitor cells by reversing their aberrant metabolic and epigenetic state.
Hosseini M, Voisin V, Chegini A, Varesi A, Cathelin S, Ayyathan DM, Liu ACH, Yang Y, Wang V, Maher A, Grignano E, Reisz JA, D'Alessandro A, Young K, Wu Y, Fiumara M, Ferrari S, Naldini L, Gaiti F, Pai S, Schimmer AD, Bader GD, Dick JE, Xie SZ, Trowbridge JJ, Chan SM. Hosseini M, et al. Among authors: trowbridge jj. Res Sq [Preprint]. 2024 Feb 6:rs.3.rs-3874821. doi: 10.21203/rs.3.rs-3874821/v1. Res Sq. 2024. PMID: 38405837 Free PMC article. Preprint.
Characterization of an Osmr Conditional Knockout Mouse Model.
Schwartz LS, Saxl RL, Stearns T, Trowbridge JJ. Schwartz LS, et al. Among authors: trowbridge jj. bioRxiv [Preprint]. 2023 Nov 1:2023.10.27.564474. doi: 10.1101/2023.10.27.564474. bioRxiv. 2023. PMID: 37961653 Free PMC article. Preprint.
Clonal hematopoiesis, aging and Alzheimer's disease.
Sánchez Vela P, Trowbridge JJ, Levine RL. Sánchez Vela P, et al. Among authors: trowbridge jj. Nat Med. 2023 Jul;29(7):1605-1606. doi: 10.1038/s41591-023-02406-4. Nat Med. 2023. PMID: 37402877 No abstract available.
Variation in histone configurations correlates with gene expression across nine inbred strains of mice.
Tyler AL, Spruce C, Kursawe R, Haber A, Ball RL, Pitman WA, Fine AD, Raghupathy N, Walker M, Philip VM, Baker CL, Mahoney JM, Churchill GA, Trowbridge JJ, Stitzel ML, Paigen K, Petkov PM, Carter GW. Tyler AL, et al. Among authors: trowbridge jj. Genome Res. 2023 Jun;33(6):857-871. doi: 10.1101/gr.277467.122. Epub 2023 May 22. Genome Res. 2023. PMID: 37217254 Free PMC article.
40 results