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Tissue-resident memory CAR T cells with stem-like characteristics display enhanced efficacy against solid and liquid tumors.
Jung IY, Noguera-Ortega E, Bartoszek R, Collins SM, Williams E, Davis M, Jadlowsky JK, Plesa G, Siegel DL, Chew A, Levine BL, Berger SL, Moon EK, Albelda SM, Fraietta JA. Jung IY, et al. Among authors: williams e. Cell Rep Med. 2023 Jun 20;4(6):101053. doi: 10.1016/j.xcrm.2023.101053. Epub 2023 May 23. Cell Rep Med. 2023. PMID: 37224816 Free PMC article.
Antigen-specific B cell depletion for precision therapy of mucosal pemphigus vulgaris.
Lee J, Lundgren DK, Mao X, Manfredo-Vieira S, Nunez-Cruz S, Williams EF, Assenmacher CA, Radaelli E, Oh S, Wang B, Ellebrecht CT, Fraietta JA, Milone MC, Payne AS. Lee J, et al. Among authors: williams ef. J Clin Invest. 2020 Dec 1;130(12):6317-6324. doi: 10.1172/JCI138416. J Clin Invest. 2020. PMID: 32817591 Free PMC article.
BET bromodomain protein inhibition reverses chimeric antigen receptor extinction and reinvigorates exhausted T cells in chronic lymphocytic leukemia.
Kong W, Dimitri A, Wang W, Jung IY, Ott CJ, Fasolino M, Wang Y, Kulikovskaya I, Gupta M, Yoder T, DeNizio JE, Everett JK, Williams EF, Xu J, Scholler J, Reich TJ, Bhoj VG, Haines KM, Maus MV, Melenhorst JJ, Young RM, Jadlowsky JK, Marcucci KT, Bradner JE, Levine BL, Porter DL, Bushman FD, Kohli RM, June CH, Davis MM, Lacey SF, Vahedi G, Fraietta JA. Kong W, et al. Among authors: williams ef. J Clin Invest. 2021 Aug 16;131(16):e145459. doi: 10.1172/JCI145459. J Clin Invest. 2021. PMID: 34396987 Free PMC article.
Type I Interferon Signaling via the EGR2 Transcriptional Regulator Potentiates CAR T Cell-Intrinsic Dysfunction.
Jung IY, Bartoszek RL, Rech AJ, Collins SM, Ooi SK, Williams EF, Hopkins CR, Narayan V, Haas NB, Frey NV, Hexner EO, Siegel DL, Plesa G, Porter DL, Cantu A, Everett JK, Guedan S, Berger SL, Bushman FD, Herbst F, Fraietta JA. Jung IY, et al. Cancer Discov. 2023 Jul 7;13(7):1636-1655. doi: 10.1158/2159-8290.CD-22-1175. Cancer Discov. 2023. PMID: 37011008 Free PMC article.
Oncogene-induced matrix reorganization controls CD8+ T cell function in the soft-tissue sarcoma microenvironment.
Fuller AM, Pruitt HC, Liu Y, Irizarry-Negron VM, Pan H, Song H, DeVine A, Katti RS, Devalaraja S, Ciotti GE, Gonzalez MV, Williams EF, Murazzi I, Ntekoumes D, Skuli N, Hakonarson H, Zabransky DJ, Trevino JG, Weeraratna A, Weber K, Haldar M, Fraietta JA, Gerecht S, Eisinger-Mathason TSK. Fuller AM, et al. Among authors: williams ef. J Clin Invest. 2024 Apr 23:e167826. doi: 10.1172/JCI167826. Online ahead of print. J Clin Invest. 2024. PMID: 38652549 Free article.
Race has no impact on prostate cancer-specific mortality, when comparing patients with similar risk of other-cause mortality: An analysis of a population-based cohort.
Tinsley SA, Finati M, Stephens A, Chiarelli G, Cirulli GO, Williams E, Morrison C, Richard C, Hares K, Sood A, Buffi N, Lughezzani G, Bettocchi C, Salonia A, Briganti A, Montorsi F, Carrieri G, Rogers C, Abdollah F. Tinsley SA, et al. Among authors: williams e. Cancer. 2024 May 28. doi: 10.1002/cncr.35386. Online ahead of print. Cancer. 2024. PMID: 38804713
HIGH THROUGHPUT QUANTITATION OF HUMAN NEUTROPHIL RECRUITMENT AND FUNCTIONAL RESPONSES IN AN AIR-BLOOD BARRIER ARRAY.
Viola H, Chen LH, Jo S, Washington K, Selva C, Li A, Feng D, Giacalone V, Stephenson ST, Cottrill K, Mohammed A, Williams E, Qu X, Lam W, Ng NL, Fitzpatrick A, Grunwell J, Tirouvanziam R, Takayama S. Viola H, et al. Among authors: williams e. bioRxiv [Preprint]. 2024 May 14:2024.05.10.593624. doi: 10.1101/2024.05.10.593624. bioRxiv. 2024. PMID: 38798413 Free PMC article. Preprint.
5,608 results