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Immune restoration by TIGIT blockade is insufficient to control chronic SIV infection.
Webb GM, Pessoa CT, McCullen AJ, Hwang JM, Humkey MC, Thormin-Odum R, Kukula KA, Smedley J, Fischer M, Sciurba J, Bochart RM, Shriver-Munsch C, Ndhlovu LC, Sacha JB. Webb GM, et al. Among authors: sciurba j. J Virol. 2024 May 22:e0027324. doi: 10.1128/jvi.00273-24. Online ahead of print. J Virol. 2024. PMID: 38775481
Eosinophil trafficking in allergen-mediated pulmonary inflammation relies on IL-13-driven CCL-11 and CCL-24 production by tissue fibroblasts and myeloid cells.
Gazzinelli-Guimaraes PH, Golec DP, Karmele EP, Sciurba J, Bara-Garcia P, Hill T, Kang B, Bennuru S, Schwartzberg PL, Nutman TB. Gazzinelli-Guimaraes PH, et al. Among authors: sciurba j. J Allergy Clin Immunol Glob. 2023 Jun 26;2(4):100131. doi: 10.1016/j.jacig.2023.100131. eCollection 2023 Nov. J Allergy Clin Immunol Glob. 2023. PMID: 37781651 Free PMC article.
Allogeneic immunity clears latent virus following allogeneic stem cell transplantation in SIV-infected ART-suppressed macaques.
Wu HL, Busman-Sahay K, Weber WC, Waytashek CM, Boyle CD, Bateman KB, Reed JS, Hwang JM, Shriver-Munsch C, Swanson T, Northrup M, Armantrout K, Price H, Robertson-LeVay M, Uttke S, Kumar MR, Fray EJ, Taylor-Brill S, Bondoc S, Agnor R, Junell SL, Legasse AW, Moats C, Bochart RM, Sciurba J, Bimber BN, Sullivan MN, Dozier B, MacAllister RP, Hobbs TR, Martin LD, Panoskaltsis-Mortari A, Colgin LMA, Siliciano RF, Siliciano JD, Estes JD, Smedley JV, Axthelm MK, Meyers G, Maziarz RT, Burwitz BJ, Stanton JJ, Sacha JB. Wu HL, et al. Among authors: sciurba j. Immunity. 2023 Jul 11;56(7):1649-1663.e5. doi: 10.1016/j.immuni.2023.04.019. Epub 2023 May 25. Immunity. 2023. PMID: 37236188
TLR5 participates in the TLR4 receptor complex and promotes MyD88-dependent signaling in environmental lung injury.
Hussain S, Johnson CG, Sciurba J, Meng X, Stober VP, Liu C, Cyphert-Daly JM, Bulek K, Qian W, Solis A, Sakamachi Y, Trempus CS, Aloor JJ, Gowdy KM, Foster WM, Hollingsworth JW, Tighe RM, Li X, Fessler MB, Garantziotis S. Hussain S, et al. Among authors: sciurba j. Elife. 2020 Jan 28;9:e50458. doi: 10.7554/eLife.50458. Elife. 2020. PMID: 31989925 Free PMC article.
17 results