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Why has model-informed precision dosing not yet become common clinical reality? lessons from the past and a roadmap for the future.
Darwich AS, Ogungbenro K, Vinks AA, Powell JR, Reny JL, Marsousi N, Daali Y, Fairman D, Cook J, Lesko LJ, McCune JS, Knibbe C, de Wildt SN, Leeder JS, Neely M, Zuppa AF, Vicini P, Aarons L, Johnson TN, Boiani J, Rostami-Hodjegan A. Darwich AS, et al. Clin Pharmacol Ther. 2017 May;101(5):646-656. doi: 10.1002/cpt.659. Epub 2017 Apr 4. Clin Pharmacol Ther. 2017. PMID: 28182269 Review.
Parametric and Nonparametric Population Pharmacokinetic Models to Assess Probability of Target Attainment of Imipenem Concentrations in Critically Ill Patients.
de Velde F, de Winter BCM, Neely MN, Strojil J, Yamada WM, Harbarth S, Huttner A, van Gelder T, Koch BCP, Muller AE, On Behalf Of The Combacte-Net Consortium. de Velde F, et al. Among authors: neely mn. Pharmaceutics. 2021 Dec 16;13(12):2170. doi: 10.3390/pharmaceutics13122170. Pharmaceutics. 2021. PMID: 34959451 Free PMC article.
Isavuconazole Pharmacokinetics and Pharmacodynamics in Children.
Elhence H, Mongkolrattanothai K, Mohandas S, Neely MN. Elhence H, et al. Among authors: neely mn. Pharmaceutics. 2022 Dec 26;15(1):75. doi: 10.3390/pharmaceutics15010075. Pharmaceutics. 2022. PMID: 36678704 Free PMC article.
Are vancomycin trough concentrations adequate for optimal dosing?
Neely MN, Youn G, Jones B, Jelliffe RW, Drusano GL, Rodvold KA, Lodise TP. Neely MN, et al. Antimicrob Agents Chemother. 2014;58(1):309-16. doi: 10.1128/AAC.01653-13. Epub 2013 Oct 28. Antimicrob Agents Chemother. 2014. PMID: 24165176 Free PMC article.
Evaluation of Vancomycin Exposures Associated with Elevations in Novel Urinary Biomarkers of Acute Kidney Injury in Vancomycin-Treated Rats.
Rhodes NJ, Prozialeck WC, Lodise TP, Venkatesan N, O'Donnell JN, Pais G, Cluff C, Lamar PC, Neely MN, Gulati A, Scheetz MH. Rhodes NJ, et al. Among authors: neely mn. Antimicrob Agents Chemother. 2016 Sep 23;60(10):5742-51. doi: 10.1128/AAC.00591-16. Print 2016 Oct. Antimicrob Agents Chemother. 2016. PMID: 27431226 Free PMC article.
217 results