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Gain-of-function IKZF1 variants in humans cause immune dysregulation associated with abnormal T/B cell late differentiation.
Hoshino A, Boutboul D, Zhang Y, Kuehn HS, Hadjadj J, Özdemir N, Celkan T, Walz C, Picard C, Lenoir C, Mahlaoui N, Klein C, Peng X, Azar A, Reigh E, Cheminant M, Fischer A, Rieux-Laucat F, Callebaut I, Hauck F, Milner J, Rosenzweig SD, Latour S. Hoshino A, et al. Among authors: hadjadj j. Sci Immunol. 2022 Mar 25;7(69):eabi7160. doi: 10.1126/sciimmunol.abi7160. Epub 2022 Mar 25. Sci Immunol. 2022. PMID: 35333544
mTOR pathway is activated in endothelial cells from patients with Takayasu arteritis and is modulated by serum immunoglobulin G.
Hadjadj J, Canaud G, Mirault T, Samson M, Bruneval P, Régent A, Goulvestre C, Witko-Sarsat V, Costedoat-Chalumeau N, Guillevin L, Mouthon L, Terrier B; French Vasculitis Study Group. Hadjadj J, et al. Rheumatology (Oxford). 2018 Jun 1;57(6):1011-1020. doi: 10.1093/rheumatology/key017. Rheumatology (Oxford). 2018. PMID: 29506143
Risk of scleroderma according to the type of immune checkpoint inhibitors.
Terrier B, Humbert S, Preta LH, Delage L, Razanamahery J, Laurent-Roussel S, Mestiri R, Beaudeau L, Legendre P, Goupil F, Hadjadj J, Stolzenberg MC, Treluyer JM, Westeel V, Valnet-Rabier MB, Wislez M, Mouthon L, Chouchana L. Terrier B, et al. Among authors: hadjadj j. Autoimmun Rev. 2020 Aug;19(8):102596. doi: 10.1016/j.autrev.2020.102596. Epub 2020 Jun 12. Autoimmun Rev. 2020. PMID: 32540450
Impaired type I interferon activity and inflammatory responses in severe COVID-19 patients.
Hadjadj J, Yatim N, Barnabei L, Corneau A, Boussier J, Smith N, Péré H, Charbit B, Bondet V, Chenevier-Gobeaux C, Breillat P, Carlier N, Gauzit R, Morbieu C, Pène F, Marin N, Roche N, Szwebel TA, Merkling SH, Treluyer JM, Veyer D, Mouthon L, Blanc C, Tharaux PL, Rozenberg F, Fischer A, Duffy D, Rieux-Laucat F, Kernéis S, Terrier B. Hadjadj J, et al. Science. 2020 Aug 7;369(6504):718-724. doi: 10.1126/science.abc6027. Epub 2020 Jul 13. Science. 2020. PMID: 32661059 Free PMC article.
Lupus Anticoagulant Single Positivity During the Acute Phase of COVID-19 Is Not Associated With Venous Thromboembolism or In-Hospital Mortality.
Gendron N, Dragon-Durey MA, Chocron R, Darnige L, Jourdi G, Philippe A, Chenevier-Gobeaux C, Hadjadj J, Duchemin J, Khider L, Yatim N, Goudot G, Krzisch D, Debuc B, Mauge L, Levavasseur F, Pene F, Boussier J, Sourdeau E, Brichet J, Ochat N, Goulvestre C, Peronino C, Szwebel TA, Pages F, Gaussem P, Samama CM, Cheurfa C, Planquette B, Sanchez O, Diehl JL, Mirault T, Fontenay M, Terrier B, Smadja DM. Gendron N, et al. Among authors: hadjadj j. Arthritis Rheumatol. 2021 Nov;73(11):1976-1985. doi: 10.1002/art.41777. Epub 2021 Sep 22. Arthritis Rheumatol. 2021. PMID: 33881229 Free PMC article.
63 results