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Single-cell transcriptomics reveal a hyperacute cytokine and immune checkpoint axis after cardiac arrest in patients with poor neurological outcome.
Tamura T, Cheng C, Chen W, Merriam LT, Athar H, Kim YH, Manandhar R, Amir Sheikh MD, Pinilla-Vera M, Varon J, Hou PC, Lawler PR, Oldham WM, Seethala RR, Tesfaigzi Y; Immunology of Cardiac Arrest Network (I-CAN); Weissman AJ, Baron RM, Ichinose F, Berg KM, Bohula EA, Morrow DA, Chen X, Kim EY. Tamura T, et al. Among authors: baron rm. Med. 2023 Jul 14;4(7):432-456.e6. doi: 10.1016/j.medj.2023.05.003. Epub 2023 May 30. Med. 2023. PMID: 37257452
Trends in "usual care" for septic shock.
Hume PS, Varon J, Englert JA, Hurwitz S, Klompas M, Baron RM, Rhee C. Hume PS, et al. Among authors: baron rm. Infect Control Hosp Epidemiol. 2018 Sep;39(9):1125-1126. doi: 10.1017/ice.2018.154. Epub 2018 Jul 19. Infect Control Hosp Epidemiol. 2018. PMID: 30022742 Free PMC article. No abstract available.
Early Neuromuscular Blockade in the Acute Respiratory Distress Syndrome.
National Heart, Lung, and Blood Institute PETAL Clinical Trials Network; Moss M, Huang DT, Brower RG, Ferguson ND, Ginde AA, Gong MN, Grissom CK, Gundel S, Hayden D, Hite RD, Hou PC, Hough CL, Iwashyna TJ, Khan A, Liu KD, Talmor D, Thompson BT, Ulysse CA, Yealy DM, Angus DC. National Heart, Lung, and Blood Institute PETAL Clinical Trials Network, et al. N Engl J Med. 2019 May 23;380(21):1997-2008. doi: 10.1056/NEJMoa1901686. Epub 2019 May 19. N Engl J Med. 2019. PMID: 31112383 Free PMC article. Clinical Trial.
Leukocyte function assessed via serial microlitre sampling of peripheral blood from sepsis patients correlates with disease severity.
Jundi B, Ryu H, Lee DH, Abdulnour RE, Engstrom BD, Duvall MG, Higuera A, Pinilla-Vera M, Benson ME, Lee J, Krishnamoorthy N, Baron RM, Han J, Voldman J, Levy BD. Jundi B, et al. Among authors: baron rm. Nat Biomed Eng. 2019 Dec;3(12):961-973. doi: 10.1038/s41551-019-0473-5. Epub 2019 Nov 11. Nat Biomed Eng. 2019. PMID: 31712645 Free PMC article.
Early High-Dose Vitamin D3 for Critically Ill, Vitamin D-Deficient Patients.
National Heart, Lung, and Blood Institute PETAL Clinical Trials Network; Ginde AA, Brower RG, Caterino JM, Finck L, Banner-Goodspeed VM, Grissom CK, Hayden D, Hough CL, Hyzy RC, Khan A, Levitt JE, Park PK, Ringwood N, Rivers EP, Self WH, Shapiro NI, Thompson BT, Yealy DM, Talmor D. National Heart, Lung, and Blood Institute PETAL Clinical Trials Network, et al. N Engl J Med. 2019 Dec 26;381(26):2529-2540. doi: 10.1056/NEJMoa1911124. Epub 2019 Dec 11. N Engl J Med. 2019. PMID: 31826336 Free PMC article. Clinical Trial.
Post-sepsis immunosuppression depends on NKT cell regulation of mTOR/IFN-γ in NK cells.
Kim EY, Ner-Gaon H, Varon J, Cullen AM, Guo J, Choi J, Barragan-Bradford D, Higuera A, Pinilla-Vera M, Short SA, Arciniegas-Rubio A, Tamura T, Leaf DE, Baron RM, Shay T, Brenner MB. Kim EY, et al. Among authors: baron rm. J Clin Invest. 2020 Jun 1;130(6):3238-3252. doi: 10.1172/JCI128075. J Clin Invest. 2020. PMID: 32154791 Free PMC article.
Plasma from patients with bacterial sepsis or severe COVID-19 induces suppressive myeloid cell production from hematopoietic progenitors in vitro.
Reyes M, Filbin MR, Bhattacharyya RP, Sonny A, Mehta A, Billman K, Kays KR, Pinilla-Vera M, Benson ME, Cosimi LA, Hung DT, Levy BD, Villani AC, Sade-Feldman M, Baron RM, Goldberg MB, Blainey PC, Hacohen N. Reyes M, et al. Among authors: baron rm. Sci Transl Med. 2021 Jun 16;13(598):eabe9599. doi: 10.1126/scitranslmed.abe9599. Epub 2021 Jun 8. Sci Transl Med. 2021. PMID: 34103408 Free PMC article.
181 results