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An ERK5-NRF2 Axis Mediates Senescence-Associated Stemness and Atherosclerosis.
Abe JI, Imanishi M, Li S, Zhang A, Ko KA, Samanthapudi VSK, Lee LL, Bojorges AP, Gi YJ, Hobbs BP, Deswal A, Herrmann J, Lin SH, Chini EN, Shen YH, Schadler KL, Nguyen TH, Gupte AA, Reyes-Gibby C, Yeung SJ, Abe RJ, Olmsted-Davis EA, Krishnan S, Dantzer R, Palaskas NL, Cooke JP, Pownall HJ, Yoshimoto M, Fujiwara K, Hamilton DJ, Burks JK, Wang G, Le NT, Kotla S. Abe JI, et al. Among authors: cooke jp. Circ Res. 2023 Jun 23;133(1):25-44. doi: 10.1161/CIRCRESAHA.122.322017. Epub 2023 Jun 2. Circ Res. 2023. PMID: 37264926 Free article.
Proton Pump Inhibitors Accelerate Endothelial Senescence.
Yepuri G, Sukhovershin R, Nazari-Shafti TZ, Petrascheck M, Ghebre YT, Cooke JP. Yepuri G, et al. Among authors: cooke jp. Circ Res. 2016 Jun 10;118(12):e36-42. doi: 10.1161/CIRCRESAHA.116.308807. Epub 2016 May 10. Circ Res. 2016. PMID: 27166251 Free PMC article.
MAGI1 as a link between endothelial activation and ER stress drives atherosclerosis.
Abe JI, Ko KA, Kotla S, Wang Y, Paez-Mayorga J, Shin IJ, Imanishi M, Vu HT, Tao Y, Leiva-Juarez MM, Thomas TN, Medina JL, Won JH, Fujii Y, Giancursio CJ, McBeath E, Shin JH, Guzman L, Abe RJ, Taunton J, Mochizuki N, Faubion W, Cooke JP, Fujiwara K, Evans SE, Le NT. Abe JI, et al. Among authors: cooke jp. JCI Insight. 2019 Apr 4;4(7):e125570. doi: 10.1172/jci.insight.125570. eCollection 2019 Apr 4. JCI Insight. 2019. PMID: 30944250 Free PMC article.
Endothelial senescence is induced by phosphorylation and nuclear export of telomeric repeat binding factor 2-interacting protein.
Kotla S, Vu HT, Ko KA, Wang Y, Imanishi M, Heo KS, Fujii Y, Thomas TN, Gi YJ, Mazhar H, Paez-Mayorga J, Shin JH, Tao Y, Giancursio CJ, Medina JL, Taunton J, Lusis AJ, Cooke JP, Fujiwara K, Le NT, Abe JI. Kotla S, et al. Among authors: cooke jp. JCI Insight. 2019 May 2;4(9):e124867. doi: 10.1172/jci.insight.124867. eCollection 2019 May 2. JCI Insight. 2019. PMID: 31045573 Free PMC article.
504 results