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An ERK5-NRF2 Axis Mediates Senescence-Associated Stemness and Atherosclerosis.
Abe JI, Imanishi M, Li S, Zhang A, Ko KA, Samanthapudi VSK, Lee LL, Bojorges AP, Gi YJ, Hobbs BP, Deswal A, Herrmann J, Lin SH, Chini EN, Shen YH, Schadler KL, Nguyen TH, Gupte AA, Reyes-Gibby C, Yeung SJ, Abe RJ, Olmsted-Davis EA, Krishnan S, Dantzer R, Palaskas NL, Cooke JP, Pownall HJ, Yoshimoto M, Fujiwara K, Hamilton DJ, Burks JK, Wang G, Le NT, Kotla S. Abe JI, et al. Among authors: ko ka. Circ Res. 2023 Jun 23;133(1):25-44. doi: 10.1161/CIRCRESAHA.122.322017. Epub 2023 Jun 2. Circ Res. 2023. PMID: 37264926 Free article.
Identification of activators of ERK5 transcriptional activity by high-throughput screening and the role of endothelial ERK5 in vasoprotective effects induced by statins and antimalarial agents.
Le NT, Takei Y, Izawa-Ishizawa Y, Heo KS, Lee H, Smrcka AV, Miller BL, Ko KA, Ture S, Morrell C, Fujiwara K, Akaike M, Abe J. Le NT, et al. Among authors: ko ka. J Immunol. 2014 Oct 1;193(7):3803-15. doi: 10.4049/jimmunol.1400571. Epub 2014 Sep 3. J Immunol. 2014. PMID: 25187658 Free PMC article.
Axl modulates immune activation of smooth muscle cells in vein graft remodeling.
Batchu SN, Xia J, Ko KA, Doyley MM, Abe J, Morrell CN, Korshunov VA. Batchu SN, et al. Among authors: ko ka. Am J Physiol Heart Circ Physiol. 2015 Sep 15;309(6):H1048-58. doi: 10.1152/ajpheart.00495.2015. Epub 2015 Aug 14. Am J Physiol Heart Circ Physiol. 2015. PMID: 26276821 Free PMC article.
En Face Preparation of Mouse Blood Vessels.
Ko KA, Fujiwara K, Krishnan S, Abe JI. Ko KA, et al. J Vis Exp. 2017 May 19;(123):55460. doi: 10.3791/55460. J Vis Exp. 2017. PMID: 28570508 Free PMC article.
MAGI1 as a link between endothelial activation and ER stress drives atherosclerosis.
Abe JI, Ko KA, Kotla S, Wang Y, Paez-Mayorga J, Shin IJ, Imanishi M, Vu HT, Tao Y, Leiva-Juarez MM, Thomas TN, Medina JL, Won JH, Fujii Y, Giancursio CJ, McBeath E, Shin JH, Guzman L, Abe RJ, Taunton J, Mochizuki N, Faubion W, Cooke JP, Fujiwara K, Evans SE, Le NT. Abe JI, et al. Among authors: ko ka. JCI Insight. 2019 Apr 4;4(7):e125570. doi: 10.1172/jci.insight.125570. eCollection 2019 Apr 4. JCI Insight. 2019. PMID: 30944250 Free PMC article.
Endothelial senescence is induced by phosphorylation and nuclear export of telomeric repeat binding factor 2-interacting protein.
Kotla S, Vu HT, Ko KA, Wang Y, Imanishi M, Heo KS, Fujii Y, Thomas TN, Gi YJ, Mazhar H, Paez-Mayorga J, Shin JH, Tao Y, Giancursio CJ, Medina JL, Taunton J, Lusis AJ, Cooke JP, Fujiwara K, Le NT, Abe JI. Kotla S, et al. Among authors: ko ka. JCI Insight. 2019 May 2;4(9):e124867. doi: 10.1172/jci.insight.124867. eCollection 2019 May 2. JCI Insight. 2019. PMID: 31045573 Free PMC article.
35 results