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Clearance of senescent macrophages ameliorates tumorigenesis in KRAS-driven lung cancer.
Haston S, Gonzalez-Gualda E, Morsli S, Ge J, Reen V, Calderwood A, Moutsopoulos I, Panousopoulos L, Deletic P, Carreno G, Guiho R, Manshaei S, Gonzalez-Meljem JM, Lim HY, Simpson DJ, Birch J, Pallikonda HA, Chandra T, Macias D, Doherty GJ, Rassl DM, Rintoul RC, Signore M, Mohorianu I, Akbar AN, Gil J, Muñoz-Espín D, Martinez-Barbera JP. Haston S, et al. Among authors: moutsopoulos i. Cancer Cell. 2023 Jul 10;41(7):1242-1260.e6. doi: 10.1016/j.ccell.2023.05.004. Epub 2023 Jun 1. Cancer Cell. 2023. PMID: 37267953 Free article.
Patterns of Oncogene Coexpression at Single-Cell Resolution Influence Survival in Lymphoma.
Hoppe MM, Jaynes P, Shuangyi F, Peng Y, Sridhar S, Hoang PM, Liu CX, De Mel S, Poon L, Chan EHL, Lee J, Ong CK, Tang T, Lim ST, Nagarajan C, Grigoropoulos NF, Tan SY, Hue SS, Chang ST, Chuang SS, Li S, Khoury JD, Choi H, Harris C, Bottos A, Gay LJ, Runge HFP, Moutsopoulos I, Mohorianu I, Hodson DJ, Farinha P, Mottok A, Scott DW, Pitt JJ, Chen J, Kumar G, Kannan K, Chng WJ, Chee YL, Ng SB, Tripodo C, Jeyasekharan AD. Hoppe MM, et al. Among authors: moutsopoulos i. Cancer Discov. 2023 May 4;13(5):1144-1163. doi: 10.1158/2159-8290.CD-22-0998. Cancer Discov. 2023. PMID: 37071673 Free PMC article.
Viral transduction of primary human lymphoma B cells reveals mechanisms of NOTCH-mediated immune escape.
Mangolini M, Maiques-Diaz A, Charalampopoulou S, Gerhard-Hartmann E, Bloehdorn J, Moore A, Giachetti G, Lu J, Roamio Franklin VN, Chilamakuri CSR, Moutsopoulos I, Rosenwald A, Stilgenbauer S, Zenz T, Mohorianu I, D'Santos C, Deaglio S, Hodson DJ, Martin-Subero JI, Ringshausen I. Mangolini M, et al. Among authors: moutsopoulos i. Nat Commun. 2022 Oct 20;13(1):6220. doi: 10.1038/s41467-022-33739-2. Nat Commun. 2022. PMID: 36266281 Free PMC article.
Myeloid cell interferon secretion restricts Zika flavivirus infection of developing and malignant human neural progenitor cells.
Bulstrode H, Girdler GC, Gracia T, Aivazidis A, Moutsopoulos I, Young AMH, Hancock J, He X, Ridley K, Xu Z, Stockley JH, Finlay J, Hallou C, Fajardo T, Fountain DM, van Dongen S, Joannides A, Morris R, Mair R, Watts C, Santarius T, Price SJ, Hutchinson PJA, Hodson EJ, Pollard SM, Mohorianu I, Barker RA, Sweeney TR, Bayraktar O, Gergely F, Rowitch DH. Bulstrode H, et al. Among authors: moutsopoulos i. Neuron. 2022 Dec 7;110(23):3936-3951.e10. doi: 10.1016/j.neuron.2022.09.002. Epub 2022 Sep 28. Neuron. 2022. PMID: 36174572 Free PMC article.