Schrom E - Search Results

1

Challenges in cybersecurity: Lessons from biological defense systems.

Schrom E, Kinzig A, Forrest S, Graham AL, Levin SA, Bergstrom CT, Castillo-Chavez C, Collins JP, de Boer RJ, Doupé A, Ensafi R, Feldman S, Grenfell BT, Halderman JA, Huijben S, Maley C, Moses M, Perelson AS, Perrings C, Plotkin J, Rexford J, Tiwari M. Schrom E, et al. Math Biosci. 2023 Aug;362:109024. doi: 10.1016/j.mbs.2023.109024. Epub 2023 Jun 2. Math Biosci. 2023. PMID: 37270102

2

Instructed subsets or agile swarms: how T-helper cells may adaptively counter uncertainty with variability and plasticity.

Schrom EC, Graham AL. Schrom EC, et al. Curr Opin Genet Dev. 2017 Dec;47:75-82. doi: 10.1016/j.gde.2017.08.008. Epub 2017 Oct 13. Curr Opin Genet Dev. 2017. PMID: 28926759 Review.

3

Quorum sensing via dynamic cytokine signaling comprehensively explains divergent patterns of effector choice among helper T cells.

Schrom EC 2nd, Levin SA, Graham AL. Schrom EC 2nd, et al. PLoS Comput Biol. 2020 Jul 30;16(7):e1008051. doi: 10.1371/journal.pcbi.1008051. eCollection 2020 Jul. PLoS Comput Biol. 2020. PMID: 32730250 Free PMC article.

4

The evolution of powerful yet perilous immune systems.

Graham AL, Schrom EC 2nd, Metcalf CJE. Graham AL, et al. Among authors: schrom ec 2nd. Trends Immunol. 2022 Feb;43(2):117-131. doi: 10.1016/j.it.2021.12.002. Epub 2021 Dec 20. Trends Immunol. 2022. PMID: 34949534 Free PMC article. Review.

5

Immune Signaling Networks: Sources of Robustness and Constrained Evolvability during Coevolution.

Schrom EC, Prada JM, Graham AL. Schrom EC, et al. Mol Biol Evol. 2018 Mar 1;35(3):676-687. doi: 10.1093/molbev/msx321. Mol Biol Evol. 2018. PMID: 29294066

6

Sarcoptic mange severity is associated with reduced genomic variation and evidence of selection in Yellowstone National Park wolves (Canis lupus).

DeCandia AL, Schrom EC, Brandell EE, Stahler DR, vonHoldt BM. DeCandia AL, et al. Among authors: schrom ec. Evol Appl. 2020 Sep 20;14(2):429-445. doi: 10.1111/eva.13127. eCollection 2021 Feb. Evol Appl. 2020. PMID: 33664786 Free PMC article.

7

Spatial Patterning Analysis of Cellular Ensembles (SPACE) enables statistically robust discovery of complex spatial organization at the cell and tissue level.

Schrom EC, McCaffrey EF, Radtke AJ, Speranza E, Arakkal L, Thakur N, Grant S, Germain RN. Schrom EC, et al. bioRxiv [Preprint]. 2023 Dec 10:2023.12.08.570837. doi: 10.1101/2023.12.08.570837. bioRxiv. 2023. PMID: 38168288 Free PMC article. Preprint.

8

TCR ligand potency differentially impacts PD-1 inhibitory effects on diverse signaling pathways.

Chan W, Cao YM, Zhao X, Schrom EC, Jia D, Song J, Sibener LV, Dong S, Fernandes RA, Bradfield CJ, Smelkinson M, Kabat J, Hor JL, Altan-Bonnet G, Garcia KC, Germain RN. Chan W, et al. Among authors: schrom ec. J Exp Med. 2023 Dec 4;220(12):e20231242. doi: 10.1084/jem.20231242. Epub 2023 Oct 5. J Exp Med. 2023. PMID: 37796477 Free PMC article.

9

A CRISPR screen targeting PI3K effectors identifies RASA3 as a negative regulator of LFA-1-mediated adhesion in T cells.

Johansen KH, Golec DP, Huang B, Park C, Thomsen JH, Preite S, Cannons JL, Garçon F, Schrom EC, Courrèges CJF, Veres TZ, Harrison J, Nus M, Phelan JD, Bergmeier W, Kehrl JH, Okkenhaug K, Schwartzberg PL. Johansen KH, et al. Among authors: schrom ec. Sci Signal. 2022 Jul 19;15(743):eabl9169. doi: 10.1126/scisignal.abl9169. Epub 2022 Jul 19. Sci Signal. 2022. PMID: 35857633 Free PMC article.

10

Understanding immunity in a tissue-centric context: Combining novel imaging methods and mathematics to extract new insights into function and dysfunction.

Germain RN, Radtke AJ, Thakur N, Schrom EC, Hor JL, Ichise H, Arroyo-Mejias AJ, Chu CJ, Grant S. Germain RN, et al. Among authors: schrom ec. Immunol Rev. 2022 Mar;306(1):8-24. doi: 10.1111/imr.13052. Epub 2021 Dec 16. Immunol Rev. 2022. PMID: 34918351 Review.

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