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Mammalian ATG8 proteins maintain autophagosomal membrane integrity through ESCRTs.
Javed R, Jain A, Duque T, Hendrix E, Paddar MA, Khan S, Claude-Taupin A, Jia J, Allers L, Wang F, Mudd M, Timmins G, Lidke K, Rusten TE, Akepati PR, He Y, Reggiori F, Eskelinen EL, Deretic V. Javed R, et al. Among authors: jain a. EMBO J. 2023 Jul 17;42(14):e112845. doi: 10.15252/embj.2022112845. Epub 2023 Jun 5. EMBO J. 2023. PMID: 37272163 Free article.
Dedicated SNAREs and specialized TRIM cargo receptors mediate secretory autophagy.
Kimura T, Jia J, Kumar S, Choi SW, Gu Y, Mudd M, Dupont N, Jiang S, Peters R, Farzam F, Jain A, Lidke KA, Adams CM, Johansen T, Deretic V. Kimura T, et al. Among authors: jain a. EMBO J. 2017 Jan 4;36(1):42-60. doi: 10.15252/embj.201695081. Epub 2016 Dec 8. EMBO J. 2017. PMID: 27932448 Free PMC article.
Mammalian hybrid pre-autophagosomal structure HyPAS generates autophagosomes.
Kumar S, Javed R, Mudd M, Pallikkuth S, Lidke KA, Jain A, Tangavelou K, Gudmundsson SR, Ye C, Rusten TE, Anonsen JH, Lystad AH, Claude-Taupin A, Simonsen A, Salemi M, Phinney B, Li J, Guo LW, Bradfute SB, Timmins GS, Eskelinen EL, Deretic V. Kumar S, et al. Among authors: jain a. Cell. 2021 Nov 24;184(24):5950-5969.e22. doi: 10.1016/j.cell.2021.10.017. Epub 2021 Nov 5. Cell. 2021. PMID: 34741801 Free PMC article.
Cellular and molecular mechanism for secretory autophagy.
Kimura T, Jia J, Claude-Taupin A, Kumar S, Choi SW, Gu Y, Mudd M, Dupont N, Jiang S, Peters R, Farzam F, Jain A, Lidke KA, Adams CM, Johansen T, Deretic V. Kimura T, et al. Among authors: jain a. Autophagy. 2017 Jun 3;13(6):1084-1085. doi: 10.1080/15548627.2017.1307486. Epub 2017 Apr 3. Autophagy. 2017. PMID: 28368721 Free PMC article.
Phosphorylation of Syntaxin 17 by TBK1 Controls Autophagy Initiation.
Kumar S, Gu Y, Abudu YP, Bruun JA, Jain A, Farzam F, Mudd M, Anonsen JH, Rusten TE, Kasof G, Ktistakis N, Lidke KA, Johansen T, Deretic V. Kumar S, et al. Among authors: jain a. Dev Cell. 2019 Apr 8;49(1):130-144.e6. doi: 10.1016/j.devcel.2019.01.027. Epub 2019 Feb 28. Dev Cell. 2019. PMID: 30827897 Free PMC article.
8,706 results