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Genome-wide Association Study for AKI.
Bhatraju PK, Stanaway IB, Palmer MR, Menon R, Schaub JA, Menez S, Srivastava A, Wilson FP, Kiryluk K, Palevsky PM, Naik AS, Sakr SS, Jarvik GP, Parikh CR, Ware LB, Ikizler TA, Siew ED, Chinchilli VM, Coca SG, Garg AX, Go AS, Kaufman JS, Kimmel PL, Himmelfarb J, Wurfel MM. Bhatraju PK, et al. Among authors: wurfel mm. Kidney360. 2023 Jul 1;4(7):870-880. doi: 10.34067/KID.0000000000000175. Epub 2023 Jun 5. Kidney360. 2023. PMID: 37273234 Free PMC article.
Toll-like receptor 1 polymorphisms affect innate immune responses and outcomes in sepsis.
Wurfel MM, Gordon AC, Holden TD, Radella F, Strout J, Kajikawa O, Ruzinski JT, Rona G, Black RA, Stratton S, Jarvik GP, Hajjar AM, Nickerson DA, Rieder M, Sevransky J, Maloney JP, Moss M, Martin G, Shanholtz C, Garcia JG, Gao L, Brower R, Barnes KC, Walley KR, Russell JA, Martin TR. Wurfel MM, et al. Am J Respir Crit Care Med. 2008 Oct 1;178(7):710-20. doi: 10.1164/rccm.200803-462OC. Epub 2008 Jul 17. Am J Respir Crit Care Med. 2008. PMID: 18635889 Free PMC article.
MCP-1 gene activation marks acute kidney injury.
Munshi R, Johnson A, Siew ED, Ikizler TA, Ware LB, Wurfel MM, Himmelfarb J, Zager RA. Munshi R, et al. Among authors: wurfel mm. J Am Soc Nephrol. 2011 Jan;22(1):165-75. doi: 10.1681/ASN.2010060641. Epub 2010 Nov 11. J Am Soc Nephrol. 2011. PMID: 21071523 Free PMC article.
ANGPT2 genetic variant is associated with trauma-associated acute lung injury and altered plasma angiopoietin-2 isoform ratio.
Meyer NJ, Li M, Feng R, Bradfield J, Gallop R, Bellamy S, Fuchs BD, Lanken PN, Albelda SM, Rushefski M, Aplenc R, Abramova H, Atochina-Vasserman EN, Beers MF, Calfee CS, Cohen MJ, Pittet JF, Christiani DC, O'Keefe GE, Ware LB, May AK, Wurfel MM, Hakonarson H, Christie JD. Meyer NJ, et al. Among authors: wurfel mm. Am J Respir Crit Care Med. 2011 May 15;183(10):1344-53. doi: 10.1164/rccm.201005-0701OC. Epub 2011 Jan 21. Am J Respir Crit Care Med. 2011. PMID: 21257790 Free PMC article.
Genome wide association identifies PPFIA1 as a candidate gene for acute lung injury risk following major trauma.
Christie JD, Wurfel MM, Feng R, O'Keefe GE, Bradfield J, Ware LB, Christiani DC, Calfee CS, Cohen MJ, Matthay M, Meyer NJ, Kim C, Li M, Akey J, Barnes KC, Sevransky J, Lanken PN, May AK, Aplenc R, Maloney JP, Hakonarson H; Trauma ALI SNP Consortium (TASC) investigators. Christie JD, et al. Among authors: wurfel mm. PLoS One. 2012;7(1):e28268. doi: 10.1371/journal.pone.0028268. Epub 2012 Jan 25. PLoS One. 2012. PMID: 22295056 Free PMC article.
Host derived biomarkers of inflammation, apoptosis, and endothelial activation are associated with clinical outcomes in patients with bacteremia and sepsis regardless of microbial etiology.
Hahn WO, Mikacenic C, Price BL, Harju-Baker S, Katz R, Himmelfarb J, Wurfel MM, Liles WC. Hahn WO, et al. Among authors: wurfel mm. Virulence. 2016 May 18;7(4):387-94. doi: 10.1080/21505594.2016.1144003. Epub 2016 Jan 28. Virulence. 2016. PMID: 26818467 Free PMC article. No abstract available.
A Two-Biomarker Model Predicts Mortality in the Critically Ill with Sepsis.
Mikacenic C, Price BL, Harju-Baker S, O'Mahony DS, Robinson-Cohen C, Radella F, Hahn WO, Katz R, Christiani DC, Himmelfarb J, Liles WC, Wurfel MM. Mikacenic C, et al. Among authors: wurfel mm. Am J Respir Crit Care Med. 2017 Oct 15;196(8):1004-1011. doi: 10.1164/rccm.201611-2307OC. Am J Respir Crit Care Med. 2017. PMID: 28418697 Free PMC article.
159 results