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Defining blood-induced microglia functions in neurodegeneration through multiomic profiling.
Mendiola AS, Yan Z, Dixit K, Johnson JR, Bouhaddou M, Meyer-Franke A, Shin MG, Yong Y, Agrawal A, MacDonald E, Muthukumar G, Pearce C, Arun N, Cabriga B, Meza-Acevedo R, Alzamora MDPS, Zamvil SS, Pico AR, Ryu JK, Krogan NJ, Akassoglou K. Mendiola AS, et al. Among authors: akassoglou k. Nat Immunol. 2023 Jul;24(7):1173-1187. doi: 10.1038/s41590-023-01522-0. Epub 2023 Jun 8. Nat Immunol. 2023. PMID: 37291385 Free PMC article.
Fibrin-targeting immunotherapy protects against neuroinflammation and neurodegeneration.
Ryu JK, Rafalski VA, Meyer-Franke A, Adams RA, Poda SB, Rios Coronado PE, Pedersen LØ, Menon V, Baeten KM, Sikorski SL, Bedard C, Hanspers K, Bardehle S, Mendiola AS, Davalos D, Machado MR, Chan JP, Plastira I, Petersen MA, Pfaff SJ, Ang KK, Hallenbeck KK, Syme C, Hakozaki H, Ellisman MH, Swanson RA, Zamvil SS, Arkin MR, Zorn SH, Pico AR, Mucke L, Freedman SB, Stavenhagen JB, Nelson RB, Akassoglou K. Ryu JK, et al. Among authors: akassoglou k. Nat Immunol. 2018 Nov;19(11):1212-1223. doi: 10.1038/s41590-018-0232-x. Epub 2018 Oct 15. Nat Immunol. 2018. PMID: 30323343 Free PMC article.
Transcriptional profiling and therapeutic targeting of oxidative stress in neuroinflammation.
Mendiola AS, Ryu JK, Bardehle S, Meyer-Franke A, Ang KK, Wilson C, Baeten KM, Hanspers K, Merlini M, Thomas S, Petersen MA, Williams A, Thomas R, Rafalski VA, Meza-Acevedo R, Tognatta R, Yan Z, Pfaff SJ, Machado MR, Bedard C, Rios Coronado PE, Jiang X, Wang J, Pleiss MA, Green AJ, Zamvil SS, Pico AR, Bruneau BG, Arkin MR, Akassoglou K. Mendiola AS, et al. Among authors: akassoglou k. Nat Immunol. 2020 May;21(5):513-524. doi: 10.1038/s41590-020-0654-0. Epub 2020 Apr 13. Nat Immunol. 2020. PMID: 32284594 Free PMC article.
Author Correction: Transcriptional profiling and therapeutic targeting of oxidative stress in neuroinflammation.
Mendiola AS, Ryu JK, Bardehle S, Meyer-Franke A, Ang KK, Wilson C, Baeten KM, Hanspers K, Merlini M, Thomas S, Petersen MA, Williams A, Thomas R, Rafalski VA, Meza-Acevedo R, Tognatta R, Yan Z, Pfaff SJ, Machado MR, Bedard C, Coronado PER, Jiang X, Wang J, Pleiss MA, Green AJ, Zamvil SS, Pico AR, Bruneau BG, Arkin MR, Akassoglou K. Mendiola AS, et al. Among authors: akassoglou k. Nat Immunol. 2020 Sep;21(9):1135. doi: 10.1038/s41590-020-0754-x. Nat Immunol. 2020. PMID: 32661365
Blood coagulation protein fibrinogen promotes autoimmunity and demyelination via chemokine release and antigen presentation.
Ryu JK, Petersen MA, Murray SG, Baeten KM, Meyer-Franke A, Chan JP, Vagena E, Bedard C, Machado MR, Rios Coronado PE, Prod'homme T, Charo IF, Lassmann H, Degen JL, Zamvil SS, Akassoglou K. Ryu JK, et al. Among authors: akassoglou k. Nat Commun. 2015 Sep 10;6:8164. doi: 10.1038/ncomms9164. Nat Commun. 2015. PMID: 26353940 Free PMC article.
Microglial Gi-dependent dynamics regulate brain network hyperexcitability.
Merlini M, Rafalski VA, Ma K, Kim KY, Bushong EA, Rios Coronado PE, Yan Z, Mendiola AS, Sozmen EG, Ryu JK, Haberl MG, Madany M, Sampson DN, Petersen MA, Bardehle S, Tognatta R, Dean T Jr, Acevedo RM, Cabriga B, Thomas R, Coughlin SR, Ellisman MH, Palop JJ, Akassoglou K. Merlini M, et al. Among authors: akassoglou k. Nat Neurosci. 2021 Jan;24(1):19-23. doi: 10.1038/s41593-020-00756-7. Epub 2020 Dec 14. Nat Neurosci. 2021. PMID: 33318667 Free PMC article.
BMP receptor blockade overcomes extrinsic inhibition of remyelination and restores neurovascular homeostasis.
Petersen MA, Tognatta R, Meyer-Franke A, Bushong EA, Mendiola AS, Yan Z, Muthusamy A, Merlini M, Meza-Acevedo R, Cabriga B, Zhou Y, Thomas R, Ryu JK, Lassmann H, Ellisman MH, Akassoglou K. Petersen MA, et al. Among authors: akassoglou k. Brain. 2021 Sep 4;144(8):2291-2301. doi: 10.1093/brain/awab106. Brain. 2021. PMID: 34426831 Free PMC article.
110 results