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Resolving sepsis-induced immunoparalysis via trained immunity by targeting interleukin-4 to myeloid cells.
Schrijver DP, Röring RJ, Deckers J, de Dreu A, Toner YC, Prevot G, Priem B, Munitz J, Nugraha EG, van Elsas Y, Azzun A, Anbergen T, Groh LA, Becker AMD, Pérez-Medina C, Oosterwijk RS, Novakovic B, Moorlag SJCFM, Jansen A, Pickkers P, Kox M, Beldman TJ, Kluza E, van Leent MMT, Teunissen AJP, van der Meel R, Fayad ZA, Joosten LAB, Fisher EA, Merkx M, Netea MG, Mulder WJM. Schrijver DP, et al. Among authors: joosten lab. Nat Biomed Eng. 2023 Sep;7(9):1097-1112. doi: 10.1038/s41551-023-01050-0. Epub 2023 Jun 8. Nat Biomed Eng. 2023. PMID: 37291433 Free PMC article.
Toll-like receptor 2 controls expansion and function of regulatory T cells.
Sutmuller RP, den Brok MH, Kramer M, Bennink EJ, Toonen LW, Kullberg BJ, Joosten LA, Akira S, Netea MG, Adema GJ. Sutmuller RP, et al. J Clin Invest. 2006 Feb;116(2):485-94. doi: 10.1172/JCI25439. Epub 2006 Jan 19. J Clin Invest. 2006. PMID: 16424940 Free PMC article.
Deficiency of interleukin-18 in mice leads to hyperphagia, obesity and insulin resistance.
Netea MG, Joosten LA, Lewis E, Jensen DR, Voshol PJ, Kullberg BJ, Tack CJ, van Krieken H, Kim SH, Stalenhoef AF, van de Loo FA, Verschueren I, Pulawa L, Akira S, Eckel RH, Dinarello CA, van den Berg W, van der Meer JW. Netea MG, et al. Nat Med. 2006 Jun;12(6):650-6. doi: 10.1038/nm1415. Epub 2006 May 28. Nat Med. 2006. PMID: 16732281
Bartonella quintana lipopolysaccharide is a natural antagonist of Toll-like receptor 4.
Popa C, Abdollahi-Roodsaz S, Joosten LA, Takahashi N, Sprong T, Matera G, Liberto MC, Foca A, van Deuren M, Kullberg BJ, van den Berg WB, van der Meer JW, Netea MG. Popa C, et al. Infect Immun. 2007 Oct;75(10):4831-7. doi: 10.1128/IAI.00237-07. Epub 2007 Jul 2. Infect Immun. 2007. PMID: 17606598 Free PMC article.
684 results