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Unraveling the genetics of arsenic toxicity with cellular morphology QTL.
O'Connor C, Keele GR, Martin W, Stodola T, Gatti D, Hoffman BR, Korstanje R, Churchill GA, Reinholdt LG. O'Connor C, et al. Among authors: reinholdt lg. PLoS Genet. 2024 Apr 25;20(4):e1011248. doi: 10.1371/journal.pgen.1011248. eCollection 2024 Apr. PLoS Genet. 2024. PMID: 38662777 Free PMC article.
An in vitro neurogenetics platform for precision disease modeling in the mouse.
Cortes DE, Escudero M, Korgan AC, Mitra A, Edwards A, Aydin SC, Munger SC, Charland K, Zhang ZW, O'Connell KMS, Reinholdt LG, Pera MF. Cortes DE, et al. Among authors: reinholdt lg. Sci Adv. 2024 Apr 5;10(14):eadj9305. doi: 10.1126/sciadv.adj9305. Epub 2024 Apr 3. Sci Adv. 2024. PMID: 38569042 Free PMC article.
Identification of robust cellular programs using reproducible LDA that impact sex-specific disease progression in different genotypes of a mouse model of AD.
Rezaie N, Rebboah E, Williams BA, Liang HY, Reese F, Balderrama-Gutierrez G, Dionne LA, Reinholdt L, Trout D, Wold BJ, Mortazavi A. Rezaie N, et al. Among authors: reinholdt l. bioRxiv [Preprint]. 2024 Feb 29:2024.02.26.582178. doi: 10.1101/2024.02.26.582178. bioRxiv. 2024. PMID: 38464087 Free PMC article. Preprint.
An allelic series of spontaneous Rorb mutant mice exhibit a gait phenotype, changes in retina morphology and behavior, and gene expression signatures associated with the unfolded protein response.
Murray GC, Bubier JA, Zinder OJ, Harris B, Clark J, Christopher MC, Hanley C, Tjong H, Li M, Ngan CY, Reinholdt L, Burgess RW, Tadenev ALD. Murray GC, et al. Among authors: reinholdt l. G3 (Bethesda). 2023 Aug 9;13(8):jkad131. doi: 10.1093/g3journal/jkad131. G3 (Bethesda). 2023. PMID: 37300435 Free PMC article.
The ENCODE4 long-read RNA-seq collection reveals distinct classes of transcript structure diversity.
Reese F, Williams B, Balderrama-Gutierrez G, Wyman D, Çelik MH, Rebboah E, Rezaie N, Trout D, Razavi-Mohseni M, Jiang Y, Borsari B, Morabito S, Liang HY, McGill CJ, Rahmanian S, Sakr J, Jiang S, Zeng W, Carvalho K, Weimer AK, Dionne LA, McShane A, Bedi K, Elhajjajy SI, Upchurch S, Jou J, Youngworth I, Gabdank I, Sud P, Jolanki O, Strattan JS, Kagda MS, Snyder MP, Hitz BC, Moore JE, Weng Z, Bennett D, Reinholdt L, Ljungman M, Beer MA, Gerstein MB, Pachter L, Guigó R, Wold BJ, Mortazavi A. Reese F, et al. Among authors: reinholdt l. bioRxiv [Preprint]. 2023 May 16:2023.05.15.540865. doi: 10.1101/2023.05.15.540865. bioRxiv. 2023. PMID: 37292896 Free PMC article. Preprint.
78 results