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DYRK1A promotes viral entry of highly pathogenic human coronaviruses in a kinase-independent manner.
Strine MS, Cai WL, Wei J, Alfajaro MM, Filler RB, Biering SB, Sarnik S, Chow RD, Patil A, Cervantes KS, Collings CK, DeWeirdt PC, Hanna RE, Schofield K, Hulme C, Konermann S, Doench JG, Hsu PD, Kadoch C, Yan Q, Wilen CB. Strine MS, et al. Among authors: doench jg. PLoS Biol. 2023 Jun 13;21(6):e3002097. doi: 10.1371/journal.pbio.3002097. eCollection 2023 Jun. PLoS Biol. 2023. PMID: 37310920 Free PMC article.
Discovery of a proteinaceous cellular receptor for a norovirus.
Orchard RC, Wilen CB, Doench JG, Baldridge MT, McCune BT, Lee YC, Lee S, Pruett-Miller SM, Nelson CA, Fremont DH, Virgin HW. Orchard RC, et al. Among authors: doench jg. Science. 2016 Aug 26;353(6302):933-6. doi: 10.1126/science.aaf1220. Epub 2016 Aug 18. Science. 2016. PMID: 27540007 Free PMC article.
A case of mistaken identity.
Hanna RE, Doench JG. Hanna RE, et al. Among authors: doench jg. Nat Biotechnol. 2018 Sep 6;36(9):802-804. doi: 10.1038/nbt.4208. Nat Biotechnol. 2018. PMID: 30188534 No abstract available.
Optimized libraries for CRISPR-Cas9 genetic screens with multiple modalities.
Sanson KR, Hanna RE, Hegde M, Donovan KF, Strand C, Sullender ME, Vaimberg EW, Goodale A, Root DE, Piccioni F, Doench JG. Sanson KR, et al. Among authors: doench jg. Nat Commun. 2018 Dec 21;9(1):5416. doi: 10.1038/s41467-018-07901-8. Nat Commun. 2018. PMID: 30575746 Free PMC article.
Design and analysis of CRISPR-Cas experiments.
Hanna RE, Doench JG. Hanna RE, et al. Among authors: doench jg. Nat Biotechnol. 2020 Jul;38(7):813-823. doi: 10.1038/s41587-020-0490-7. Epub 2020 Apr 13. Nat Biotechnol. 2020. PMID: 32284587 Review.
Optimization of AsCas12a for combinatorial genetic screens in human cells.
DeWeirdt PC, Sanson KR, Sangree AK, Hegde M, Hanna RE, Feeley MN, Griffith AL, Teng T, Borys SM, Strand C, Joung JK, Kleinstiver BP, Pan X, Huang A, Doench JG. DeWeirdt PC, et al. Among authors: doench jg. Nat Biotechnol. 2021 Jan;39(1):94-104. doi: 10.1038/s41587-020-0600-6. Epub 2020 Jul 13. Nat Biotechnol. 2021. PMID: 32661438 Free PMC article.
173 results