Hargreaves DC - Search Results

1

Canonical BAF complex activity shapes the enhancer landscape that licenses CD8⁺ T cell effector and memory fates.

McDonald B, Chick BY, Ahmed NS, Burns M, Ma S, Casillas E, Chen D, Mann TH, O'Connor C, Hah N, Hargreaves DC, Kaech SM. McDonald B, et al. Among authors: hargreaves dc. Immunity. 2023 Jun 13;56(6):1303-1319.e5. doi: 10.1016/j.immuni.2023.05.005. Immunity. 2023. PMID: 37315534

2

A Genome-wide CRISPR Screen Reveals a Role for the Non-canonical Nucleosome-Remodeling BAF Complex in Foxp3 Expression and Regulatory T Cell Function.

Loo CS, Gatchalian J, Liang Y, Leblanc M, Xie M, Ho J, Venkatraghavan B, Hargreaves DC, Zheng Y. Loo CS, et al. Among authors: hargreaves dc. Immunity. 2020 Jul 14;53(1):143-157.e8. doi: 10.1016/j.immuni.2020.06.011. Epub 2020 Jul 7. Immunity. 2020. PMID: 32640256 Free PMC article.

3

BRD9 regulates interferon-stimulated genes during macrophage activation via cooperation with BET protein BRD4.

Ahmed NS, Gatchalian J, Ho J, Burns MJ, Hah N, Wei Z, Downes M, Evans RM, Hargreaves DC. Ahmed NS, et al. Among authors: hargreaves dc. Proc Natl Acad Sci U S A. 2022 Jan 4;119(1):e2110812119. doi: 10.1073/pnas.2110812119. Proc Natl Acad Sci U S A. 2022. PMID: 34983841 Free PMC article.

4

Switching under selection: how CoREST controls endocrine therapy resistance in ER⁺ breast cancer.

Chick BY, Hargreaves DC. Chick BY, et al. Among authors: hargreaves dc. Nat Struct Mol Biol. 2022 Nov;29(11):1040-1042. doi: 10.1038/s41594-022-00858-9. Nat Struct Mol Biol. 2022. PMID: 36344845 No abstract available.

5

Manipulating mitochondrial electron flow enhances tumor immunogenicity.

Mangalhara KC, Varanasi SK, Johnson MA, Burns MJ, Rojas GR, Esparza Moltó PB, Sainz AG, Tadepalle N, Abbott KL, Mendiratta G, Chen D, Farsakoglu Y, Kunchok T, Hoffmann FA, Parisi B, Rincon M, Vander Heiden MG, Bosenberg M, Hargreaves DC, Kaech SM, Shadel GS. Mangalhara KC, et al. Among authors: hargreaves dc. Science. 2023 Sep 22;381(6664):1316-1323. doi: 10.1126/science.abq1053. Epub 2023 Sep 21. Science. 2023. PMID: 37733872 Free PMC article.

6

RNA polymerase II promoter-proximal pausing promotes BAF chromatin binding and remodeling.

Chick BY, Hargreaves DC. Chick BY, et al. Among authors: hargreaves dc. Nat Genet. 2024 Jan;56(1):19-20. doi: 10.1038/s41588-023-01628-z. Nat Genet. 2024. PMID: 38129539 No abstract available.

7

Early Chromatin Remodeling Events in Acutely Stimulated CD8⁺ T Cells.

McDonald B, Chick BY, Hargreaves DC, Kaech SM. McDonald B, et al. Among authors: hargreaves dc. Yale J Biol Med. 2023 Dec 29;96(4):467-473. doi: 10.59249/AXGU7370. eCollection 2023 Dec. Yale J Biol Med. 2023. PMID: 38161581 Free PMC article.

8

ARID1A suppresses R-loop-mediated STING-type I interferon pathway activation of anti-tumor immunity.

Maxwell MB, Hom-Tedla MS, Yi J, Li S, Rivera SA, Yu J, Burns MJ, McRae HM, Stevenson BT, Coakley KE, Ho J, Gastelum KB, Bell JC, Jones AC, Eskander RN, Dykhuizen EC, Shadel GS, Kaech SM, Hargreaves DC. Maxwell MB, et al. Among authors: hargreaves dc. Cell. 2024 May 9:S0092-8674(24)00451-3. doi: 10.1016/j.cell.2024.04.025. Online ahead of print. Cell. 2024. PMID: 38754421

9

Racheting Up Repair.

Gatchalian J, Hargreaves DC. Gatchalian J, et al. Among authors: hargreaves dc. Immunity. 2018 Oct 16;49(4):577-579. doi: 10.1016/j.immuni.2018.09.012. Immunity. 2018. PMID: 30332621 Free article.

10

A non-canonical BRD9-containing BAF chromatin remodeling complex regulates naive pluripotency in mouse embryonic stem cells.

Gatchalian J, Malik S, Ho J, Lee DS, Kelso TWR, Shokhirev MN, Dixon JR, Hargreaves DC. Gatchalian J, et al. Among authors: hargreaves dc. Nat Commun. 2018 Dec 3;9(1):5139. doi: 10.1038/s41467-018-07528-9. Nat Commun. 2018. PMID: 30510198 Free PMC article.

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