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Defective extracellular matrix remodeling in brown adipose tissue is associated with fibro-inflammation and reduced diet-induced thermogenesis.
Pellegrinelli V, Figueroa-Juárez E, Samuelson I, U-Din M, Rodriguez-Fdez S, Virtue S, Leggat J, Çubuk C, Peirce VJ, Niemi T, Campbell M, Rodriguez-Cuenca S, Blázquez JD, Carobbio S, Virtanen KA, Vidal-Puig A. Pellegrinelli V, et al. Among authors: virtue s. Cell Rep. 2023 Jun 27;42(6):112640. doi: 10.1016/j.celrep.2023.112640. Epub 2023 Jun 13. Cell Rep. 2023. PMID: 37318951 Free article.
The link between nutritional status and insulin sensitivity is dependent on the adipocyte-specific peroxisome proliferator-activated receptor-gamma2 isoform.
Medina-Gomez G, Virtue S, Lelliott C, Boiani R, Campbell M, Christodoulides C, Perrin C, Jimenez-Linan M, Blount M, Dixon J, Zahn D, Thresher RR, Aparicio S, Carlton M, Colledge WH, Kettunen MI, Seppänen-Laakso T, Sethi JK, O'Rahilly S, Brindle K, Cinti S, Oresic M, Burcelin R, Vidal-Puig A. Medina-Gomez G, et al. Among authors: virtue s. Diabetes. 2005 Jun;54(6):1706-16. doi: 10.2337/diabetes.54.6.1706. Diabetes. 2005. PMID: 15919792 Free PMC article.
PPAR gamma 2 prevents lipotoxicity by controlling adipose tissue expandability and peripheral lipid metabolism.
Medina-Gomez G, Gray SL, Yetukuri L, Shimomura K, Virtue S, Campbell M, Curtis RK, Jimenez-Linan M, Blount M, Yeo GS, Lopez M, Seppänen-Laakso T, Ashcroft FM, Oresic M, Vidal-Puig A. Medina-Gomez G, et al. Among authors: virtue s. PLoS Genet. 2007 Apr 27;3(4):e64. doi: 10.1371/journal.pgen.0030064. PLoS Genet. 2007. PMID: 17465682 Free PMC article.
It's not how fat you are, it's what you do with it that counts.
Virtue S, Vidal-Puig A. Virtue S, et al. PLoS Biol. 2008 Sep 23;6(9):e237. doi: 10.1371/journal.pbio.0060237. PLoS Biol. 2008. PMID: 18816166 Free PMC article.
Mechanisms underlying obesity-related metabolic disorders are poorly understood. Samuel Virtue and Antonio Vidal-Puig explore the evidence for an emerging hypothesis that attributes metabolic complications not to obesity per se, but to an individual's capacity for a …
Mechanisms underlying obesity-related metabolic disorders are poorly understood. Samuel Virtue and Antonio Vidal-Puig explore the evi …
Secreted frizzled-related protein 1 regulates adipose tissue expansion and is dysregulated in severe obesity.
Lagathu C, Christodoulides C, Tan CY, Virtue S, Laudes M, Campbell M, Ishikawa K, Ortega F, Tinahones FJ, Fernández-Real JM, Orešič M, Sethi JK, Vidal-Puig A. Lagathu C, et al. Among authors: virtue s. Int J Obes (Lond). 2010 Dec;34(12):1695-705. doi: 10.1038/ijo.2010.107. Epub 2010 Jun 1. Int J Obes (Lond). 2010. PMID: 20514047 Free PMC article.
120 results