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Estrogen receptor 1 chromatin profiling in human breast tumors reveals high inter-patient heterogeneity with enrichment of risk SNPs and enhancer activity at most-conserved regions.
Joosten SEP, Gregoricchio S, Stelloo S, Yapıcı E, Huang CF, Yavuz K, Donaldson Collier M, Morova T, Altintaş UB, Kim Y, Canisius S, Moelans CB, van Diest PJ, Korkmaz G, Lack NA, Vermeulen M, Linn SC, Zwart W. Joosten SEP, et al. Genome Res. 2024 May 15;34(4):539-555. doi: 10.1101/gr.278680.123. Genome Res. 2024. PMID: 38719469
Mtb HLA-E-tetramer-sorted CD8+ T cells have a diverse TCR repertoire.
Voogd L, Drittij AMHF, Dingenouts CKE, Franken KLMC, Unen VV, van Meijgaarden KE, Ruibal P, Hagedoorn RS, Leitner JA, Steinberger P, Heemskerk MHM, Davis MM, Scriba TJ, Ottenhoff THM, Joosten SA. Voogd L, et al. Among authors: joosten sa. iScience. 2024 Feb 15;27(3):109233. doi: 10.1016/j.isci.2024.109233. eCollection 2024 Mar 15. iScience. 2024. PMID: 38439958 Free PMC article.
Lymphopenia is associated with broad host response aberrations in community-acquired pneumonia.
Doeleman SE, Reijnders TDY, Joosten SCM, Schuurman AR, van Engelen TSR, Verhoeff J, Léopold V, Brands X, Haak BW, Prins JM, Kanglie MMNP, van den Berk IAH, Faber DR, Douma RA, Stoker J, Saris A, Garcia Vallejo JJ, Wiersinga WJ, van der Poll T. Doeleman SE, et al. Among authors: joosten scm. J Infect. 2024 Apr;88(4):106131. doi: 10.1016/j.jinf.2024.106131. Epub 2024 Feb 29. J Infect. 2024. PMID: 38431153 Free article.
The shifting lipidomic landscape of blood monocytes and neutrophils during pneumonia.
Schuurman AR, Chouchane O, Butler JM, Peters-Sengers H, Joosten S, Brands X, Haak BW, Otto NA, Uhel F, Klarenbeek A, van Linge CC, van Kampen A, Pras-Raves M, van Weeghel M, van Eijk M, Ferraz MJ, Faber DR, de Vos A, Scicluna BP, Vaz FM, Wiersinga WJ, van der Poll T. Schuurman AR, et al. Among authors: joosten s. JCI Insight. 2024 Feb 22;9(4):e164400. doi: 10.1172/jci.insight.164400. JCI Insight. 2024. PMID: 38385743 Free PMC article.
Staring us in the face: resumption of CPAP therapy.
Joosten SA, Genta PR. Joosten SA, et al. Eur Respir J. 2024 Feb 1;63(2):2302213. doi: 10.1183/13993003.02213-2023. Print 2024 Feb. Eur Respir J. 2024. PMID: 38302178 No abstract available.
BCG vaccination-induced acquired control of mycobacterial growth differs from growth control preexisting to BCG vaccination.
van Meijgaarden KE, Li W, Moorlag SJCFM, Koeken VACM, Koenen HJPM, Joosten LAB, Vyakarnam A, Ahmed A, Rakshit S, Adiga V, Ottenhoff THM, Li Y, Netea MG, Joosten SA. van Meijgaarden KE, et al. Among authors: joosten sa. Nat Commun. 2024 Jan 2;15(1):114. doi: 10.1038/s41467-023-44252-5. Nat Commun. 2024. PMID: 38167829 Free PMC article.
The MHC-E peptide ligands for checkpoint CD94/NKG2A are governed by inflammatory signals, whereas LILRB1/2 receptors are peptide indifferent.
Middelburg J, Ghaffari S, Schoufour TAW, Sluijter M, Schaap G, Göynük B, Sala BM, Al-Tamimi L, Scheeren F, Franken KLMC, Akkermans JJLL, Cabukusta B, Joosten SA, Derksen I, Neefjes J, van der Burg SH, Achour A, Wijdeven RHM, Weidanz J, van Hall T. Middelburg J, et al. Among authors: joosten sa. Cell Rep. 2023 Dec 26;42(12):113516. doi: 10.1016/j.celrep.2023.113516. Epub 2023 Dec 3. Cell Rep. 2023. PMID: 38048225 Free article.
Breast cancer risk SNPs converge on estrogen receptor binding sites commonly shared between breast tumors to locally alter estrogen signalling output.
Joosten SE, Gregoricchio S, Stelloo S, Yapıcı E, Huang CF, Collier MD, Morova T, Altintas B, Kim Y, Canisius S, Korkmaz G, Lack N, Vermeulen M, Linn SC, Zwart W. Joosten SE, et al. bioRxiv [Preprint]. 2023 Nov 2:2023.10.30.564691. doi: 10.1101/2023.10.30.564691. bioRxiv. 2023. PMID: 37961147 Free PMC article. Preprint.
Airway epithelial cells mount an early response to mycobacterial infection.
Barclay AM, Ninaber DK, van Veen S, Hiemstra PS, Ottenhoff THM, van der Does AM, Joosten SA. Barclay AM, et al. Among authors: joosten sa. Front Cell Infect Microbiol. 2023 Sep 26;13:1253037. doi: 10.3389/fcimb.2023.1253037. eCollection 2023. Front Cell Infect Microbiol. 2023. PMID: 37822359 Free PMC article.
261 results