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Phase 1 trial evaluating safety and pharmacokinetics of HIV-1 broadly neutralizing mAbs 10E8VLS and VRC07-523LS.
JCI Insight. 2024 Apr 8;9(7):e175375. doi: 10.1172/jci.insight.175375.
JCI Insight. 2024.
PMID: 38587079
Free PMC article.
Clinical Trial.
Trispecific antibody targeting HIV-1 and T cells activates and eliminates latently-infected cells in HIV/SHIV infections.
Promsote W, Xu L, Hataye J, Fabozzi G, March K, Almasri CG, DeMouth ME, Lovelace SE, Talana CA, Doria-Rose NA, McKee K, Hait SH, Casazza JP, Ambrozak D, Beninga J, Rao E, Furtmann N, Birkenfeld J, McCarthy E, Todd JP, Petrovas C, Connors M, Hebert AT, Beck J, Shen J, Zhang B, Levit M, Wei RR, Yang ZY, Pegu A, Mascola JR, Nabel GJ, Koup RA.
Promsote W, et al. Among authors: almasri cg.
Nat Commun. 2023 Jun 22;14(1):3719. doi: 10.1038/s41467-023-39265-z.
Nat Commun. 2023.
PMID: 37349337
Free PMC article.
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Potent anti-viral activity of a trispecific HIV neutralizing antibody in SHIV-infected monkeys.
Pegu A, Xu L, DeMouth ME, Fabozzi G, March K, Almasri CG, Cully MD, Wang K, Yang ES, Dias J, Fennessey CM, Hataye J, Wei RR, Rao E, Casazza JP, Promsote W, Asokan M, McKee K, Schmidt SD, Chen X, Liu C, Shi W, Geng H, Foulds KE, Kao SF, Noe A, Li H, Shaw GM, Zhou T, Petrovas C, Todd JP, Keele BF, Lifson JD, Doria-Rose NA, Koup RA, Yang ZY, Nabel GJ, Mascola JR.
Pegu A, et al. Among authors: almasri cg.
Cell Rep. 2022 Jan 4;38(1):110199. doi: 10.1016/j.celrep.2021.110199.
Cell Rep. 2022.
PMID: 34986348
Free PMC article.
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Concordance of immunological events between intrarectal and intravenous SHIVAD8-EO infection when assessed by Fiebig-equivalent staging.
Dias J, Fabozzi G, March K, Asokan M, Almasri CG, Fintzi J, Promsote W, Nishimura Y, Todd JP, Lifson JD, Martin MA, Gama L, Petrovas C, Pegu A, Mascola JR, Koup RA.
Dias J, et al. Among authors: almasri cg.
J Clin Invest. 2021 Sep 1;131(17):e151632. doi: 10.1172/JCI151632.
J Clin Invest. 2021.
PMID: 34623326
Free PMC article.
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Anti-HIV-1 Antibodies: An Update.
Promsote W, DeMouth ME, Almasri CG, Pegu A.
Promsote W, et al. Among authors: almasri cg.
BioDrugs. 2020 Apr;34(2):121-132. doi: 10.1007/s40259-020-00413-2.
BioDrugs. 2020.
PMID: 32152957
Review.
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