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Page 1
Defining a longevity biotechnology company.
Boekstein N, Barzilai N, Bertram A, Betts-LaCroix J, Fortney K, Helliwell SB, Hufford M, Mannick J, McLaughlin J, Mellon J, Morgen E, Regge N, Robinton DA, Sinclair DA, Young S, Starr R, Zhavoronkov A, Peyer J. Boekstein N, et al. Among authors: sinclair da. Nat Biotechnol. 2023 Aug;41(8):1053-1055. doi: 10.1038/s41587-023-01854-0. Nat Biotechnol. 2023. PMID: 37365260 No abstract available.
ARDD 2020: from aging mechanisms to interventions.
Mkrtchyan GV, Abdelmohsen K, Andreux P, Bagdonaite I, Barzilai N, Brunak S, Cabreiro F, de Cabo R, Campisi J, Cuervo AM, Demaria M, Ewald CY, Fang EF, Faragher R, Ferrucci L, Freund A, Silva-García CG, Georgievskaya A, Gladyshev VN, Glass DJ, Gorbunova V, de Grey A, He WW, Hoeijmakers J, Hoffmann E, Horvath S, Houtkooper RH, Jensen MK, Jensen MB, Kane A, Kassem M, de Keizer P, Kennedy B, Karsenty G, Lamming DW, Lee KF, MacAulay N, Mamoshina P, Mellon J, Molenaars M, Moskalev A, Mund A, Niedernhofer L, Osborne B, Pak HH, Parkhitko A, Raimundo N, Rando TA, Rasmussen LJ, Reis C, Riedel CG, Franco-Romero A, Schumacher B, Sinclair DA, Suh Y, Taub PR, Toiber D, Treebak JT, Valenzano DR, Verdin E, Vijg J, Young S, Zhang L, Bakula D, Zhavoronkov A, Scheibye-Knudsen M. Mkrtchyan GV, et al. Among authors: sinclair da. Aging (Albany NY). 2020 Dec 30;12(24):24484-24503. doi: 10.18632/aging.202454. Epub 2020 Dec 30. Aging (Albany NY). 2020. PMID: 33378272 Free PMC article. Review.
Advanced pathological ageing should be represented in the ICD.
Bischof E, Maier AB, Lee KF, Zhavoronkov A, Sinclair D. Bischof E, et al. Lancet Healthy Longev. 2022 Jan;3(1):e12. doi: 10.1016/S2666-7568(21)00303-2. Lancet Healthy Longev. 2022. PMID: 36098284 Free article. No abstract available.
Resveratrol Improves Vascular Function and Mitochondrial Number but Not Glucose Metabolism in Older Adults.
Pollack RM, Barzilai N, Anghel V, Kulkarni AS, Golden A, O'Broin P, Sinclair DA, Bonkowski MS, Coleville AJ, Powell D, Kim S, Moaddel R, Stein D, Zhang K, Hawkins M, Crandall JP. Pollack RM, et al. Among authors: sinclair da. J Gerontol A Biol Sci Med Sci. 2017 Nov 9;72(12):1703-1709. doi: 10.1093/gerona/glx041. J Gerontol A Biol Sci Med Sci. 2017. PMID: 28329397 Free PMC article. Clinical Trial.
Resveratrol improves health and survival of mice on a high-calorie diet.
Baur JA, Pearson KJ, Price NL, Jamieson HA, Lerin C, Kalra A, Prabhu VV, Allard JS, Lopez-Lluch G, Lewis K, Pistell PJ, Poosala S, Becker KG, Boss O, Gwinn D, Wang M, Ramaswamy S, Fishbein KW, Spencer RG, Lakatta EG, Le Couteur D, Shaw RJ, Navas P, Puigserver P, Ingram DK, de Cabo R, Sinclair DA. Baur JA, et al. Among authors: sinclair da. Nature. 2006 Nov 16;444(7117):337-42. doi: 10.1038/nature05354. Epub 2006 Nov 1. Nature. 2006. PMID: 17086191 Free PMC article.
The longevity of sirtuins.
Sinclair D, Verdin E. Sinclair D, et al. Cell Rep. 2012 Dec 27;2(6):1473-4. doi: 10.1016/j.celrep.2012.12.004. Cell Rep. 2012. PMID: 23273894 Free article.
Reprogramming to recover youthful epigenetic information and restore vision.
Lu Y, Brommer B, Tian X, Krishnan A, Meer M, Wang C, Vera DL, Zeng Q, Yu D, Bonkowski MS, Yang JH, Zhou S, Hoffmann EM, Karg MM, Schultz MB, Kane AE, Davidsohn N, Korobkina E, Chwalek K, Rajman LA, Church GM, Hochedlinger K, Gladyshev VN, Horvath S, Levine ME, Gregory-Ksander MS, Ksander BR, He Z, Sinclair DA. Lu Y, et al. Among authors: sinclair da. Nature. 2020 Dec;588(7836):124-129. doi: 10.1038/s41586-020-2975-4. Epub 2020 Dec 2. Nature. 2020. PMID: 33268865 Free PMC article.
The Information Theory of Aging.
Lu YR, Tian X, Sinclair DA. Lu YR, et al. Among authors: sinclair da. Nat Aging. 2023 Dec;3(12):1486-1499. doi: 10.1038/s43587-023-00527-6. Epub 2023 Dec 15. Nat Aging. 2023. PMID: 38102202 Review.
TIME-seq reduces time and cost of DNA methylation measurement for epigenetic clock construction.
Griffin PT, Kane AE, Trapp A, Li J, Arnold M, Poganik JR, Conway RJ, McNamara MS, Meer MV, Hoffman N, Amorim JA, Tian X, MacArthur MR, Mitchell SJ, Mueller AL, Carmody C, Vera DL, Kerepesi C, Ying K, Noren Hooten N, Mitchell JR, Evans MK, Gladyshev VN, Sinclair DA. Griffin PT, et al. Among authors: sinclair da. Nat Aging. 2024 Feb;4(2):261-274. doi: 10.1038/s43587-023-00555-2. Epub 2024 Jan 10. Nat Aging. 2024. PMID: 38200273
277 results