Oxidative processing of latent Fas in the endoplasmic reticulum controls the strength of apoptosis.
Anathy V, Roberson E, Cunniff B, Nolin JD, Hoffman S, Spiess P, Guala AS, Lahue KG, Goldman D, Flemer S, van der Vliet A, Heintz NH, Budd RC, Tew KD, Janssen-Heininger YM.
Anathy V, et al.
Mol Cell Biol. 2012 Sep;32(17):3464-78. doi: 10.1128/MCB.00125-12. Epub 2012 Jul 2.
Mol Cell Biol. 2012.
PMID: 22751926
Free PMC article.
We recently demonstrated that S-glutathionylation of the death receptor Fas (Fas-SSG) amplifies apoptosis (V. Anathy et al., J. Cell Biol. 184:241-252, 2009). In the present study, we demonstrate that distinct pools of Fas exist in cells. ...
We recently demonstrated that S-glutathionylation of the death receptor Fas (Fas-SSG) amplifies apoptosis (V. Anathy et al., J …