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Notch signaling drives intestinal graft-versus-host disease in mice and nonhuman primates.
Tkachev V, Vanderbeck A, Perkey E, Furlan SN, McGuckin C, Gómez Atria D, Gerdemann U, Rui X, Lane J, Hunt DJ, Zheng H, Colonna L, Hoffman M, Yu A, Outen R, Kelly S, Allman A, Koch U, Radtke F, Ludewig B, Burbach B, Shimizu Y, Panoskaltsis-Mortari A, Chen G, Carpenter SM, Harari O, Kuhnert F, Thurston G, Blazar BR, Kean LS, Maillard I. Tkachev V, et al. Among authors: ludewig b. Sci Transl Med. 2023 Jun 28;15(702):eadd1175. doi: 10.1126/scitranslmed.add1175. Epub 2023 Jun 28. Sci Transl Med. 2023. PMID: 37379368
Fibroblastic niches prime T cell alloimmunity through Delta-like Notch ligands.
Chung J, Ebens CL, Perkey E, Radojcic V, Koch U, Scarpellino L, Tong A, Allen F, Wood S, Feng J, Friedman A, Granadier D, Tran IT, Chai Q, Onder L, Yan M, Reddy P, Blazar BR, Huang AY, Brennan TV, Bishop DK, Ludewig B, Siebel CW, Radtke F, Luther SA, Maillard I. Chung J, et al. Among authors: ludewig b. J Clin Invest. 2017 Apr 3;127(4):1574-1588. doi: 10.1172/JCI89535. Epub 2017 Mar 20. J Clin Invest. 2017. PMID: 28319044 Free PMC article.
GCNT1-Mediated O-Glycosylation of the Sialomucin CD43 Is a Sensitive Indicator of Notch Signaling in Activated T Cells.
Perkey E, Maurice De Sousa D, Carrington L, Chung J, Dils A, Granadier D, Koch U, Radtke F, Ludewig B, Blazar BR, Siebel CW, Brennan TV, Nolz J, Labrecque N, Maillard I. Perkey E, et al. Among authors: ludewig b. J Immunol. 2020 Mar 15;204(6):1674-1688. doi: 10.4049/jimmunol.1901194. Epub 2020 Feb 14. J Immunol. 2020. PMID: 32060138 Free PMC article.
Stromal Notch ligands foster lymphopenia-driven functional plasticity and homeostatic proliferation of naive B cells.
Gómez Atria D, Gaudette BT, Londregan J, Kelly S, Perkey E, Allman A, Srivastava B, Koch U, Radtke F, Ludewig B, Siebel CW, Ryan RJ, Robertson TF, Burkhardt JK, Pear WS, Allman D, Maillard I. Gómez Atria D, et al. Among authors: ludewig b. J Clin Invest. 2022 Jul 1;132(13):e158885. doi: 10.1172/JCI158885. J Clin Invest. 2022. PMID: 35579963 Free PMC article.
A novel cryopreservation and biobanking strategy to study lymphoid tissue stromal cells in human disease.
Brandstadter JD, De Martin A, Lϋtge M, Ferreira A, Gaudette BT, Stanossek Y, Wang S, Gonzalez MV, Camiolo E, Wertheim G, Austin B, Allman D, Bagg A, Lim MS, Fajgenbaum DC, Aster JC, Ludewig B, Maillard I. Brandstadter JD, et al. Among authors: ludewig b. Eur J Immunol. 2023 Sep;53(9):e2250362. doi: 10.1002/eji.202250362. Epub 2023 Jun 27. Eur J Immunol. 2023. PMID: 37366295
Protective fibroblastic niches in secondary lymphoid organs.
De Martin A, Stanossek Y, Pikor NB, Ludewig B. De Martin A, et al. Among authors: ludewig b. J Exp Med. 2024 Jan 1;221(1):e20221220. doi: 10.1084/jem.20221220. Epub 2023 Dec 1. J Exp Med. 2024. PMID: 38038708 Free PMC article. Review.
Fibroblast-derived IL-33 is dispensable for lymph node homeostasis but critical for CD8 T-cell responses to acute and chronic viral infection.
Aparicio-Domingo P, Cannelle H, Buechler MB, Nguyen S, Kallert SM, Favre S, Alouche N, Papazian N, Ludewig B, Cupedo T, Pinschewer DD, Turley SJ, Luther SA. Aparicio-Domingo P, et al. Among authors: ludewig b. Eur J Immunol. 2021 Jan;51(1):76-90. doi: 10.1002/eji.201948413. Epub 2020 Aug 5. Eur J Immunol. 2021. PMID: 32700362 Free article.
223 results