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Graft dysfunction in compassionate use of genetically engineered pig-to-human cardiac xenotransplantation: a case report.
Mohiuddin MM, Singh AK, Scobie L, Goerlich CE, Grazioli A, Saharia K, Crossan C, Burke A, Drachenberg C, Oguz C, Zhang T, Lewis B, Hershfeld A, Sentz F, Tatarov I, Mudd S, Braileanu G, Rice K, Paolini JF, Bondensgaard K, Vaught T, Kuravi K, Sorrells L, Dandro A, Ayares D, Lau C, Griffith BP. Mohiuddin MM, et al. Among authors: goerlich ce. Lancet. 2023 Jul 29;402(10399):397-410. doi: 10.1016/S0140-6736(23)00775-4. Epub 2023 Jun 29. Lancet. 2023. PMID: 37393920
Regulatory barriers to xenotransplantation.
Goerlich CE, Chan JL, Mohiuddin MM. Goerlich CE, et al. Curr Opin Organ Transplant. 2019 Oct;24(5):522-526. doi: 10.1097/MOT.0000000000000678. Curr Opin Organ Transplant. 2019. PMID: 31361629 Free PMC article. Review.
Blood Cardioplegia Induction, Perfusion Storage and Graft Dysfunction in Cardiac Xenotransplantation.
Goerlich CE, Griffith B, Singh AK, Abdullah M, Singireddy S, Kolesnik I, Lewis B, Sentz F, Tatarov I, Hershfeld A, Zhang T, Strauss E, Odonkor P, Williams B, Tabatabai A, Bhutta A, Ayares D, Kaczorowski DJ, Mohiuddin MM. Goerlich CE, et al. Front Immunol. 2021 Jun 9;12:667093. doi: 10.3389/fimmu.2021.667093. eCollection 2021. Front Immunol. 2021. PMID: 34177906 Free PMC article.
An intrinsic link to an extrinsic cause of cardiac xenograft growth after xenotransplantation: Commentary (in response to): Zaman, R. et al. Selective loss of resident macrophage-derived insulin-like growth factor-1 abolishes adaptive cardiac growth to stress. Immunity 54, 2057-2071.e6 (2021).: Commentary (in response to): Zaman, R. et al. Selective loss of resident macrophage-derived insulin-like growth factor-1 abolishes adaptive cardiac growth to stress. Immunity 54, 2057-2071.e6 (2021).
Goerlich CE, Singh A, Treffalls JA, Griffith B, Ayares D, Mohiuddin MM. Goerlich CE, et al. Xenotransplantation. 2022 Jan;29(1):e12724. doi: 10.1111/xen.12724. Epub 2022 Jan 10. Xenotransplantation. 2022. PMID: 35001436 Free PMC article.
Progressive genetic modifications of porcine cardiac xenografts extend survival to 9 months.
Mohiuddin MM, Goerlich CE, Singh AK, Zhang T, Tatarov I, Lewis B, Sentz F, Hershfeld A, Braileanu G, Odonkor P, Strauss E, Williams B, Burke A, Hittman J, Bhutta A, Tabatabai A, Gupta A, Vaught T, Sorrells L, Kuravi K, Dandro A, Eyestone W, Kaczorowski DJ, Ayares D, Griffith BP. Mohiuddin MM, et al. Among authors: goerlich ce. Xenotransplantation. 2022 May;29(3):e12744. doi: 10.1111/xen.12744. Epub 2022 Mar 31. Xenotransplantation. 2022. PMID: 35357044 Free PMC article.
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