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Graft dysfunction in compassionate use of genetically engineered pig-to-human cardiac xenotransplantation: a case report.
Mohiuddin MM, Singh AK, Scobie L, Goerlich CE, Grazioli A, Saharia K, Crossan C, Burke A, Drachenberg C, Oguz C, Zhang T, Lewis B, Hershfeld A, Sentz F, Tatarov I, Mudd S, Braileanu G, Rice K, Paolini JF, Bondensgaard K, Vaught T, Kuravi K, Sorrells L, Dandro A, Ayares D, Lau C, Griffith BP. Mohiuddin MM, et al. Among authors: sorrells l. Lancet. 2023 Jul 29;402(10399):397-410. doi: 10.1016/S0140-6736(23)00775-4. Epub 2023 Jun 29. Lancet. 2023. PMID: 37393920
Allergic response to medical products in patients with alpha-gal syndrome.
Kuravi KV, Sorrells LT, Nellis JR, Rahman F, Walters AH, Matheny RG, Choudhary SK, Ayares DL, Commins SP, Bianchi JR, Turek JW. Kuravi KV, et al. Among authors: sorrells lt. J Thorac Cardiovasc Surg. 2022 Dec;164(6):e411-e424. doi: 10.1016/j.jtcvs.2021.03.100. Epub 2021 Apr 9. J Thorac Cardiovasc Surg. 2022. PMID: 33933257 Free PMC article.
Humanized von Willebrand factor reduces platelet sequestration in ex vivo and in vivo xenotransplant models.
Connolly MR, Kuravi K, Burdorf L, Sorrells L, Morrill B, Cimeno A, Vaught T, Dandro A, Sendil S, Habibabady ZA, Monahan J, Li T, LaMattina J, Eyestone W, Ayares D, Phelps C, Azimzadeh AM, Pierson RN 3rd. Connolly MR, et al. Among authors: sorrells l. Xenotransplantation. 2021 Nov;28(6):e12712. doi: 10.1111/xen.12712. Epub 2021 Oct 17. Xenotransplantation. 2021. PMID: 34657336 Free PMC article.
hEPCR.hTBM.hCD47.hHO-1 with donor clodronate and DDAVP treatment improves perfusion and function of GalTKO.hCD46 porcine livers perfused with human blood.
Cimeno A, Kuravi K, Sorrells L, Dandro A, Sendil S, Burdorf L, Parsell DM, Eyestone W, Phelps C, Ayares D, Azimzadeh AM, Pierson RN 3rd, Barth RN, LaMattina JC. Cimeno A, et al. Among authors: sorrells l. Xenotransplantation. 2022 Mar;29(2):e12731. doi: 10.1111/xen.12731. Epub 2022 Feb 15. Xenotransplantation. 2022. PMID: 35166407 Free PMC article.
Effects of human TFPI and CD47 expression and selectin and integrin inhibition during GalTKO.hCD46 pig lung perfusion with human blood.
Miura S, Habibabady ZA, Pollok F, Connolly M, Pratts S, Dandro A, Sorrells L, Karavi K, Phelps C, Eyestone W, Ayares D, Burdorf L, Azimzadeh A, Pierson RN 3rd. Miura S, et al. Among authors: sorrells l. Xenotransplantation. 2022 Mar;29(2):e12725. doi: 10.1111/xen.12725. Epub 2022 Mar 2. Xenotransplantation. 2022. PMID: 35234315 Free PMC article.
Progressive genetic modifications of porcine cardiac xenografts extend survival to 9 months.
Mohiuddin MM, Goerlich CE, Singh AK, Zhang T, Tatarov I, Lewis B, Sentz F, Hershfeld A, Braileanu G, Odonkor P, Strauss E, Williams B, Burke A, Hittman J, Bhutta A, Tabatabai A, Gupta A, Vaught T, Sorrells L, Kuravi K, Dandro A, Eyestone W, Kaczorowski DJ, Ayares D, Griffith BP. Mohiuddin MM, et al. Among authors: sorrells l. Xenotransplantation. 2022 May;29(3):e12744. doi: 10.1111/xen.12744. Epub 2022 Mar 31. Xenotransplantation. 2022. PMID: 35357044 Free PMC article.
Pig-to-human heart xenotransplantation in two recently deceased human recipients.
Moazami N, Stern JM, Khalil K, Kim JI, Narula N, Mangiola M, Weldon EP, Kagermazova L, James L, Lawson N, Piper GL, Sommer PM, Reyentovich A, Bamira D, Saraon T, Kadosh BS, DiVita M, Goldberg RI, Hussain ST, Chan J, Ngai J, Jan T, Ali NM, Tatapudi VS, Segev DL, Bisen S, Jaffe IS, Piegari B, Kowalski H, Kokkinaki M, Monahan J, Sorrells L, Burdorf L, Boeke JD, Pass H, Goparaju C, Keating B, Ayares D, Lorber M, Griesemer A, Mehta SA, Smith DE, Montgomery RA. Moazami N, et al. Among authors: sorrells l. Nat Med. 2023 Aug;29(8):1989-1997. doi: 10.1038/s41591-023-02471-9. Epub 2023 Jul 24. Nat Med. 2023. PMID: 37488288
Consistent survival in consecutive cases of life-supporting porcine kidney xenotransplantation using 10GE source pigs.
Eisenson D, Hisadome Y, Santillan M, Iwase H, Chen W, Shimizu A, Schulick A, Gu D, Akbar A, Zhou A, Koenig K, Kuravi K, Rahman F, Sorrells L, Burdorf L, DeSmet K, Warren D, Peterson L, Lorber M, Ayares D, Cameron A, Yamada K. Eisenson D, et al. Among authors: sorrells l. Nat Commun. 2024 Apr 18;15(1):3361. doi: 10.1038/s41467-024-47679-6. Nat Commun. 2024. PMID: 38637524 Free PMC article.
Binder-Jet 3D Printing of Indomethacin-laden Pharmaceutical Dosage Forms.
Chang SY, Li SW, Kowsari K, Shetty A, Sorrells L, Sen K, Nagapudi K, Chaudhuri B, Ma AWK. Chang SY, et al. Among authors: sorrells l. J Pharm Sci. 2020 Oct;109(10):3054-3063. doi: 10.1016/j.xphs.2020.06.027. Epub 2020 Jul 3. J Pharm Sci. 2020. PMID: 32628950
12 results