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Graft dysfunction in compassionate use of genetically engineered pig-to-human cardiac xenotransplantation: a case report.
Mohiuddin MM, Singh AK, Scobie L, Goerlich CE, Grazioli A, Saharia K, Crossan C, Burke A, Drachenberg C, Oguz C, Zhang T, Lewis B, Hershfeld A, Sentz F, Tatarov I, Mudd S, Braileanu G, Rice K, Paolini JF, Bondensgaard K, Vaught T, Kuravi K, Sorrells L, Dandro A, Ayares D, Lau C, Griffith BP. Mohiuddin MM, et al. Among authors: zhang t. Lancet. 2023 Jul 29;402(10399):397-410. doi: 10.1016/S0140-6736(23)00775-4. Epub 2023 Jun 29. Lancet. 2023. PMID: 37393920
Life-supporting function of genetically modified swine lungs in baboons.
Nguyen BN, Azimzadeh AM, Zhang T, Wu G, Schuurman HJ, Sachs DH, Ayares D, Allan JS, Pierson RN 3rd. Nguyen BN, et al. Among authors: zhang t. J Thorac Cardiovasc Surg. 2007 May;133(5):1354-63. doi: 10.1016/j.jtcvs.2006.11.043. Epub 2007 Apr 2. J Thorac Cardiovasc Surg. 2007. PMID: 17467457 Free article.
Pig-to-baboon liver xenoperfusion utilizing GalTKO.hCD46 pigs and glycoprotein Ib blockade.
LaMattina JC, Burdorf L, Zhang T, Rybak E, Cheng X, Munivenkatappa R, Salles II, Broos K, Sievert E, McCormick B, Decarlo M, Ayares D, Deckmyn H, Azimzadeh AM, Pierson RN 3rd, Barth RN. LaMattina JC, et al. Among authors: zhang t. Xenotransplantation. 2014 May-Jun;21(3):274-86. doi: 10.1111/xen.12093. Epub 2014 Mar 17. Xenotransplantation. 2014. PMID: 24628649 Free PMC article.
Early graft failure of GalTKO pig organs in baboons is reduced by expression of a human complement pathway-regulatory protein.
Azimzadeh AM, Kelishadi SS, Ezzelarab MB, Singh AK, Stoddard T, Iwase H, Zhang T, Burdorf L, Sievert E, Avon C, Cheng X, Ayares D, Horvath KA, Corcoran PC, Mohiuddin MM, Barth RN, Cooper DK, Pierson RN 3rd. Azimzadeh AM, et al. Among authors: zhang t. Xenotransplantation. 2015 Jul-Aug;22(4):310-6. doi: 10.1111/xen.12176. Epub 2015 Jul 14. Xenotransplantation. 2015. PMID: 26174749 Free PMC article.
Preemptive CD20+ B cell Depletion Attenuates Cardiac Allograft Vasculopathy in CD154-Treated Monkeys.
Azimzadeh AM, Zhang T, Wu G, Kelishadi SS, Stoddard T, OʼNeill N, Nguyen BN, Welty E, Avon C, Higuchi M, Mitchell SL, Hershfeld A, Cheng XF, Kronfli A, Rybak E, Burdorf L, Pierson RN 3rd. Azimzadeh AM, et al. Among authors: zhang t. Transplantation. 2017 Jan;101(1):63-73. doi: 10.1097/TP.0000000000001258. Transplantation. 2017. PMID: 27362307 Free PMC article.
Comparative Evaluation of αCD40 (2C10R4) and αCD154 (5C8H1 and IDEC-131) in a Nonhuman Primate Cardiac Allotransplant Model.
OʼNeill NA, Zhang T, Braileanu G, Sun W, Cheng X, Hershfeld A, Laird CT, Kronfli A, Hock LA, Dahi S, Kubicki N, Sievert E, Hassanein W, Cimeno A, Pierson RN 3rd, Azimzadeh AM. OʼNeill NA, et al. Among authors: zhang t. Transplantation. 2017 Sep;101(9):2038-2047. doi: 10.1097/TP.0000000000001836. Transplantation. 2017. PMID: 28557955 Free PMC article.
Pilot Study of Delayed ICOS/ICOS-L Blockade With αCD40 to Modulate Pathogenic Alloimmunity in a Primate Cardiac Allograft Model.
O'Neill NA, Zhang T, Braileanu G, Cheng X, Hershfeld A, Sun W, Reimann KA, Dahi S, Kubicki N, Hassanein W, Laird C, Cimeno A, Azimzadeh AM, Pierson RN. O'Neill NA, et al. Among authors: zhang t. Transplant Direct. 2018 Feb 2;4(2):e344. doi: 10.1097/TXD.0000000000000761. eCollection 2018 Feb. Transplant Direct. 2018. PMID: 29464205 Free PMC article.
Thromboxane and histamine mediate PVR elevation during xenogeneic pig lung perfusion with human blood.
Burdorf L, Harris D, Dahi S, Laird C, Zhang T, Ali F, Shah A, Thompson M, Braileanu G, Cheng X, Sievert E, Schwartz E, Sendil S, Parsell DM, Redding E, Phelps CJ, Ayares DL, Azimzadeh AM, Pierson RN 3rd. Burdorf L, et al. Among authors: zhang t. Xenotransplantation. 2019 Mar;26(2):e12458. doi: 10.1111/xen.12458. Epub 2018 Sep 3. Xenotransplantation. 2019. PMID: 30175863 Free PMC article.
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