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Multiplex single-cell chemical genomics reveals the kinase dependence of the response to targeted therapy.
McFaline-Figueroa JL, Srivatsan S, Hill AJ, Gasperini M, Jackson DL, Saunders L, Domcke S, Regalado SG, Lazarchuck P, Alvarez S, Monnat RJ Jr, Shendure J, Trapnell C. McFaline-Figueroa JL, et al. Among authors: shendure j. bioRxiv [Preprint]. 2023 Jun 14:2023.03.10.531983. doi: 10.1101/2023.03.10.531983. bioRxiv. 2023. PMID: 37398090 Free PMC article. Updated. Preprint.
Modulation of FGF pathway signaling and vascular differentiation using designed oligomeric assemblies.
Edman NI, Redler RL, Phal A, Schlichthaerle T, Srivatsan SR, Etemadi A, An SJ, Favor A, Ehnes D, Li Z, Praetorius F, Gordon M, Yang W, Coventry B, Hicks DR, Cao L, Bethel N, Heine P, Murray A, Gerben S, Carter L, Miranda M, Negahdari B, Lee S, Trapnell C, Stewart L, Ekiert DC, Schlessinger J, Shendure J, Bhabha G, Ruohola-Baker H, Baker D. Edman NI, et al. Among authors: shendure j. bioRxiv [Preprint]. 2023 Mar 15:2023.03.14.532666. doi: 10.1101/2023.03.14.532666. bioRxiv. 2023. PMID: 36993355 Free PMC article. Preprint.
GENOME REPORT: Chromosome-scale genome assembly of the African spiny mouse ( Acomys cahirinus ).
Nguyen ED, Fard VN, Kim BY, Collins S, Galey M, Nelson BR, Wakenight P, Gable SM, McKenna A, Bammler TK, MacDonald J, Okamura DM, Shendure J, Beier DR, Ramirez JM, Majesky MW, Millen KJ, Tollis M, Miller DE. Nguyen ED, et al. Among authors: shendure j. bioRxiv [Preprint]. 2023 Apr 5:2023.04.03.535372. doi: 10.1101/2023.04.03.535372. bioRxiv. 2023. PMID: 37066261 Free PMC article. Updated. Preprint.
A single-cell transcriptional timelapse of mouse embryonic development, from gastrula to pup.
Qiu C, Martin BK, Welsh IC, Daza RM, Le TM, Huang X, Nichols EK, Taylor ML, Fulton O, O'Day DR, Gomes AR, Ilcisin S, Srivatsan S, Deng X, Disteche CM, Noble WS, Hamazaki N, Moens CB, Kimelman D, Cao J, Schier AF, Spielmann M, Murray SA, Trapnell C, Shendure J. Qiu C, et al. Among authors: shendure j. bioRxiv [Preprint]. 2023 Apr 5:2023.04.05.535726. doi: 10.1101/2023.04.05.535726. bioRxiv. 2023. PMID: 37066300 Free PMC article. Updated. Preprint.
Predicting cellular responses to complex perturbations in high-throughput screens.
Lotfollahi M, Klimovskaia Susmelj A, De Donno C, Hetzel L, Ji Y, Ibarra IL, Srivatsan SR, Naghipourfar M, Daza RM, Martin B, Shendure J, McFaline-Figueroa JL, Boyeau P, Wolf FA, Yakubova N, Günnemann S, Trapnell C, Lopez-Paz D, Theis FJ. Lotfollahi M, et al. Among authors: shendure j. Mol Syst Biol. 2023 Jun 12;19(6):e11517. doi: 10.15252/msb.202211517. Epub 2023 May 8. Mol Syst Biol. 2023. PMID: 37154091 Free PMC article.
Proteostasis governs differential temperature sensitivity across embryonic cell types.
Dorrity MW, Saunders LM, Duran M, Srivatsan SR, Barkan E, Jackson DL, Sattler SM, Ewing B, Queitsch C, Shendure J, Raible DW, Kimelman D, Trapnell C. Dorrity MW, et al. Among authors: shendure j. Cell. 2023 Nov 9;186(23):5015-5027.e12. doi: 10.1016/j.cell.2023.10.013. Cell. 2023. PMID: 37949057 Free article.
432 results