Bazin HG - Search Results

1

A lipidated TLR7/8 adjuvant enhances the efficacy of a vaccine against fentanyl in mice.

Miller SM, Crouse B, Hicks L, Amin H, Cole S, Bazin HG, Burkhart DJ, Pravetoni M, Evans JT. Miller SM, et al. Among authors: bazin hg. NPJ Vaccines. 2023 Jul 10;8(1):97. doi: 10.1038/s41541-023-00694-y. NPJ Vaccines. 2023. PMID: 37429853 Free PMC article.

2

Characterization of TRIF selectivity in the AGP class of lipid A mimetics: role of secondary lipid chains.

Khalaf JK, Bowen WS, Bazin HG, Ryter KT, Livesay MT, Ward JR, Evans JT, Johnson DA. Khalaf JK, et al. Among authors: bazin hg. Bioorg Med Chem Lett. 2015 Feb 1;25(3):547-53. doi: 10.1016/j.bmcl.2014.12.024. Epub 2014 Dec 17. Bioorg Med Chem Lett. 2015. PMID: 25553892 Free PMC article.

3

Structural requirements for TLR7-selective signaling by 9-(4-piperidinylalkyl)-8-oxoadenine derivatives.

Bazin HG, Li Y, Khalaf JK, Mwakwari S, Livesay MT, Evans JT, Johnson DA. Bazin HG, et al. Bioorg Med Chem Lett. 2015 Mar 15;25(6):1318-23. doi: 10.1016/j.bmcl.2015.01.037. Epub 2015 Jan 31. Bioorg Med Chem Lett. 2015. PMID: 25698055 Free PMC article.

4

Evaluation of novel synthetic TLR7/8 agonists as vaccine adjuvants.

Smith AJ, Li Y, Bazin HG, St-Jean JR, Larocque D, Evans JT, Baldridge JR. Smith AJ, et al. Among authors: bazin hg. Vaccine. 2016 Aug 5;34(36):4304-12. doi: 10.1016/j.vaccine.2016.06.080. Epub 2016 Jul 9. Vaccine. 2016. PMID: 27402566 Free PMC article.

5

Synthetic Toll-like Receptors 7 and 8 Agonists: Structure-Activity Relationship in the Oxoadenine Series.

Evans JT, Bess LS, Mwakwari SC, Livesay MT, Li Y, Cybulski V, Johnson DA, Bazin HG. Evans JT, et al. Among authors: bazin hg. ACS Omega. 2019 Sep 10;4(13):15665-15677. doi: 10.1021/acsomega.9b02138. eCollection 2019 Sep 24. ACS Omega. 2019. PMID: 31572869 Free PMC article.

6

Co-encapsulation of synthetic lipidated TLR4 and TLR7/8 agonists in the liposomal bilayer results in a rapid, synergistic enhancement of vaccine-mediated humoral immunity.

Short KK, Miller SM, Walsh L, Cybulski V, Bazin H, Evans JT, Burkhart D. Short KK, et al. J Control Release. 2019 Dec 10;315:186-196. doi: 10.1016/j.jconrel.2019.10.025. Epub 2019 Oct 22. J Control Release. 2019. PMID: 31654684 Free PMC article.

7

Optimization of 8-oxoadenines with toll-like-receptor 7 and 8 activity.

Bazin HG, Bess LS, Livesay MT, Li Y, Cybulski V, Miller SM, Johnson DA, Evans JT. Bazin HG, et al. Bioorg Med Chem Lett. 2020 Mar 15;30(6):126984. doi: 10.1016/j.bmcl.2020.126984. Epub 2020 Jan 22. Bioorg Med Chem Lett. 2020. PMID: 32001135 Free PMC article.

8

Novel Lipidated Imidazoquinoline TLR7/8 Adjuvants Elicit Influenza-Specific Th1 Immune Responses and Protect Against Heterologous H3N2 Influenza Challenge in Mice.

Miller SM, Cybulski V, Whitacre M, Bess LS, Livesay MT, Walsh L, Burkhart D, Bazin HG, Evans JT. Miller SM, et al. Among authors: bazin hg. Front Immunol. 2020 Mar 10;11:406. doi: 10.3389/fimmu.2020.00406. eCollection 2020. Front Immunol. 2020. PMID: 32210973 Free PMC article.

9

A tractable covalent linker strategy for the production of immunogenic antigen-TLR7/8L bioconjugates.

Massena CJ, Lathrop SK, Davison CJ, Schoener R, Bazin HG, Evans JT, Burkhart DJ. Massena CJ, et al. Among authors: bazin hg. Chem Commun (Camb). 2021 May 11;57(38):4698-4701. doi: 10.1039/d1cc00795e. Chem Commun (Camb). 2021. PMID: 33977971 Free PMC article.

10

Development of a TLR7/8 agonist adjuvant formulation to overcome early life hyporesponsiveness to DTaP vaccination.

Dowling DJ, Barman S, Smith AJ, Borriello F, Chaney D, Brightman SE, Melhem G, Brook B, Menon M, Soni D, Schüller S, Siram K, Nanishi E, Bazin HG, Burkhart DJ, Levy O, Evans JT. Dowling DJ, et al. Among authors: bazin hg. Sci Rep. 2022 Oct 18;12(1):16860. doi: 10.1038/s41598-022-20346-w. Sci Rep. 2022. PMID: 36258023 Free PMC article.

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