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Structure-based discovery of thiosemicarbazones as SARS-CoV-2 main protease inhibitors.
Maltarollo VG, da Silva EB, Kronenberger T, Sena Andrade MM, de Lima Marques GV, Cândido Oliveira NJ, Santos LH, Oliveira Rezende Júnior C, Cassiano Martinho AC, Skinner D, Fajtová P, M Fernandes TH, Silveira Dos Santos ED, Rodrigues Gazolla PA, Martins de Souza AP, da Silva ML, Dos Santos FS, Lavorato SN, Oliveira Bretas AC, Carvalho DT, Franco LL, Luedtke S, Giardini MA, Poso A, Dias LC, Podust LM, Alves RJ, McKerrow J, Andrade SF, Teixeira RR, Siqueira-Neto JL, O'Donoghue A, de Oliveira RB, Ferreira RS. Maltarollo VG, et al. Among authors: alves rj. Future Med Chem. 2023 Jun;15(11):959-985. doi: 10.4155/fmc-2023-0034. Epub 2023 Jul 12. Future Med Chem. 2023. PMID: 37435731
Synthesis and evaluation of the anti parasitic activity of aromatic nitro compounds.
Lopes MS, de Souza Pietra RC, Borgati TF, Romeiro CF, Júnior PA, Romanha AJ, Alves RJ, Souza-Fagundes EM, Fernandes AP, de Oliveira RB. Lopes MS, et al. Among authors: alves rj. Eur J Med Chem. 2011 Nov;46(11):5443-7. doi: 10.1016/j.ejmech.2011.09.002. Epub 2011 Sep 8. Eur J Med Chem. 2011. PMID: 21940071
Synthesis of nitroaromatic compounds as potential anticancer agents.
Lopes MS, de Andrade Sena CF, Silva BL, de Souza CM, Ramos JP, Cassali GD, de Souza-Fagundes EM, Alves RJ, de Oliveira MC, de Oliveira RB. Lopes MS, et al. Among authors: alves rj. Anticancer Agents Med Chem. 2015;15(2):206-16. doi: 10.2174/1871520614666141114201749. Anticancer Agents Med Chem. 2015. PMID: 25403167
Synthesis of a sugar-based thiosemicarbazone series and structure-activity relationship versus the parasite cysteine proteases rhodesain, cruzain, and Schistosoma mansoni cathepsin B1.
Fonseca NC, da Cruz LF, da Silva Villela F, do Nascimento Pereira GA, de Siqueira-Neto JL, Kellar D, Suzuki BM, Ray D, de Souza TB, Alves RJ, Sales Júnior PA, Romanha AJ, Murta SM, McKerrow JH, Caffrey CR, de Oliveira RB, Ferreira RS. Fonseca NC, et al. Among authors: alves rj. Antimicrob Agents Chemother. 2015 May;59(5):2666-77. doi: 10.1128/AAC.04601-14. Epub 2015 Feb 23. Antimicrob Agents Chemother. 2015. PMID: 25712353 Free PMC article.
An effective in vitro and in vivo antileishmanial activity and mechanism of action of 8-hydroxyquinoline against Leishmania species causing visceral and tegumentary leishmaniasis.
Costa Duarte M, dos Reis Lage LM, Lage DP, Mesquita JT, Salles BC, Lavorato SN, Menezes-Souza D, Roatt BM, Alves RJ, Tavares CA, Tempone AG, Coelho EA. Costa Duarte M, et al. Among authors: alves rj. Vet Parasitol. 2016 Feb 15;217:81-8. doi: 10.1016/j.vetpar.2016.01.002. Epub 2016 Jan 7. Vet Parasitol. 2016. PMID: 26827866
1,3-Bis(aryloxy)propan-2-ols as potential antileishmanial agents.
Lavorato SN, Duarte MC, Lage DP, Tavares CAP, Coelho EAF, Alves RJ. Lavorato SN, et al. Among authors: alves rj. Chem Biol Drug Des. 2017 Nov;90(5):981-986. doi: 10.1111/cbdd.13024. Epub 2017 Jun 28. Chem Biol Drug Des. 2017. PMID: 28590516 Free PMC article.
142 results