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High-throughput Oligopaint screen identifies druggable 3D genome regulators.
Park DS, Nguyen SC, Isenhart R, Shah PP, Kim W, Barnett RJ, Chandra A, Luppino JM, Harke J, Wai M, Walsh PJ, Abdill RJ, Yang R, Lan Y, Yoon S, Yunker R, Kanemaki MT, Vahedi G, Phillips-Cremins JE, Jain R, Joyce EF. Park DS, et al. Among authors: joyce ef. Nature. 2023 Aug;620(7972):209-217. doi: 10.1038/s41586-023-06340-w. Epub 2023 Jul 12. Nature. 2023. PMID: 37438531
Targeted demethylation at the CDKN1C/p57 locus induces human β cell replication.
Ou K, Yu M, Moss NG, Wang YJ, Wang AW, Nguyen SC, Jiang C, Feleke E, Kameswaran V, Joyce EF, Naji A, Glaser B, Avrahami D, Kaestner KH. Ou K, et al. Among authors: joyce ef. J Clin Invest. 2019 Jan 2;129(1):209-214. doi: 10.1172/JCI99170. Epub 2018 Nov 26. J Clin Invest. 2019. PMID: 30352048 Free PMC article.
Oncogenic Notch Promotes Long-Range Regulatory Interactions within Hyperconnected 3D Cliques.
Petrovic J, Zhou Y, Fasolino M, Goldman N, Schwartz GW, Mumbach MR, Nguyen SC, Rome KS, Sela Y, Zapataro Z, Blacklow SC, Kruhlak MJ, Shi J, Aster JC, Joyce EF, Little SC, Vahedi G, Pear WS, Faryabi RB. Petrovic J, et al. Among authors: joyce ef. Mol Cell. 2019 Mar 21;73(6):1174-1190.e12. doi: 10.1016/j.molcel.2019.01.006. Epub 2019 Feb 7. Mol Cell. 2019. PMID: 30745086 Free PMC article.
ARID1A spatially partitions interphase chromosomes.
Wu S, Fatkhutdinov N, Rosin L, Luppino JM, Iwasaki O, Tanizawa H, Tang HY, Kossenkov AV, Gardini A, Noma KI, Speicher DW, Joyce EF, Zhang R. Wu S, et al. Among authors: joyce ef. Sci Adv. 2019 May 22;5(5):eaaw5294. doi: 10.1126/sciadv.aaw5294. eCollection 2019 May. Sci Adv. 2019. PMID: 31131328 Free PMC article.
Programmable Chromosome Painting with Oligopaints.
Nguyen SC, Joyce EF. Nguyen SC, et al. Among authors: joyce ef. Methods Mol Biol. 2019;2038:167-180. doi: 10.1007/978-1-4939-9674-2_11. Methods Mol Biol. 2019. PMID: 31407284 Free PMC article.
48 results